Vergleich

Goat Anti-CDH23 / USH1D Antibody

ArtNr ABC-AF1220a
Hersteller Abcepta
Menge 100 ug
Kategorie
Typ Antibody Primary
Applikationen WB, ELISA
Specific against other
Host Goat
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Similar products CDH23, KIAA1774, KIAA1812, Otocadherin, Cadherin-23
Lieferbar
Primary Accession
Q9H251
Antigen Type
Synthetic Peptide
Application
WB, E
Bio Background
This gene is a member of the cadherin superfamily, whose genes encode calcium dependent cell-cell adhesion glycoproteins. The encoded protein is thought to be involved in stereocilia organization and hair bundle formation. The gene is located in a region containing the human deafness loci DFNB12 and USH1D. Usher syndrome 1D and nonsyndromic autosomal recessive deafness DFNB12 are caused by allelic mutations of this cadherin-like gene. Alternative splice variants encoding different isoforms have been described.
Bio References
Structure of the N terminus of cadherin 23 reveals a new adhesion mechanism for a subset of cadherin superfamily members. Elledge HM, et al. Proc Natl Acad Sci U S A, 2010 Jun 8. PMID 20498078.
Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. Rose JE, et al. Mol Med, 2010 Jul-Aug. PMID 20379614.
Microarray-based mutation analysis of 183 Spanish families with Usher syndrome. Jaijo T, et al. Invest Ophthalmol Vis Sci, 2010 Mar. PMID 19683999.
Assembling stable hair cell tip link complex via multidentate interactions between harmonin and cadherin 23. Pan L, et al. Proc Natl Acad Sci U S A, 2009 Apr 7. PMID 19297620.
Genome-wide association study of smoking initiation and current smoking. Vink JM, et al. Am J Hum Genet, 2009 Mar. PMID 19268276.
Clonality
Polyclonal
Gene ID
64072
Gene Name
CDH23 {ECO:0000303|PubMed:11138009, ECO:0000312|HGNC:HGNC:13733}
Subtitle
Peptide-affinity purified goat antibody
Reactivity
H
Legend image 1
AF1220a (1 µg/ml) staining of Human Amygdala lysate (35 µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
Type image 1
WB
Other Accession
NP_443068; 64072;
Concentration (mg/ml)
100ug/200ul

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 100 ug
Lieferbar: In stock
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