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Goat Anti-KCNQ1 Antibody

Goat Anti-KCNQ1 Antibody

ArtNr	ABC-AF1587a
Hersteller	Abcepta
Menge	100 ug
Kategorie	Antibodies Primary Antibodies
Typ	Antibody Primary
Applikationen	WB, ELISA
Specific against	other
Host	Goat
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Similar products	KCNQ1, KCNA8, KCNA9, KVLQT1, Potassium voltage-gated channel subfamily KQT member 1, IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1, KQT-like 1, Voltage-gated potassium channel subunit Kv7.1
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Primary Accession	P51787
Antigen Type	Synthetic Peptide
Application	WB, E
Bio Background	This gene encodes a protein for a voltage-gated potassium channel required for the repolarization phase of the cardiac action potential. The gene product can form heteromultimers with two other potassium channel proteins, KCNE1 and KCNE3. Mutations in this gene are associated with hereditary long QT syndrome, Romano-Ward syndrome, Jervell and Lange-Nielsen syndrome and familial atrial fibrillation. The gene is located in a region of chromosome 11 that contains a large number of contiguous genes that are abnormally imprinted in cancer and the Beckwith-Wiedemann syndrome. Two alternative transcripts encoding distinct isoforms have been described.
Bio References	Obesity and diabetes genetic variants associated with gestational weight gain. Stuebe AM, et al. Am J Obstet Gynecol, 2010 Sep. PMID 20816152. Glycemia determines the effect of type 2 diabetes risk genes on insulin secretion. Heni M, et al. Diabetes, 2010 Aug 29. PMID 20802253. KCNQ1 gene polymorphisms are associated with lipid parameters in a Chinese Han population. Chen Z, et al. Cardiovasc Diabetol, 2010 Aug 11. PMID 20701788. COMMON VARIANTS IN 40 GENES ASSESSED FOR DIABETES INCIDENCE AND RESPONSE TO METFORMIN AND LIFESTYLE INTERVENTIONS IN THE DIABETES PREVENTION PROGRAM. Jablonski KA, et al. Diabetes, 2010 Aug 3. PMID 20682687. Variation at the NFATC2 Locus Increases the Risk of Thiazolinedinedione-Induced Edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) Study. Bailey SD, et al. Diabetes Care, 2010 Jul 13. PMID 20628086.
Clonality	Polyclonal
Gene ID	3784
Gene Name	KCNQ1 (HGNC:6294)
Subtitle	Peptide-affinity purified goat antibody
Reactivity	H
Legend image 1	AF1587a (1 µg/ml) staining of Human Heart lysate (35 µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
Type image 1	WB
Other Accession	NP_861463; 3784; 16535 (mouse); 84020 (rat);
Predicted	M, Rat, Dog, Cow
Concentration (mg/ml)	0.5 mg/ml

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ABC-AF1587a-datasheet.pdf

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Menge: 100 ug

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Lieferung vsl. bis 04.09.2025

Express-Lieferung: 1 Tage sparen

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