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Goat Anti-Thioredoxin Reductase 1 Antibody

Goat Anti-Thioredoxin Reductase 1 Antibody

ArtNr	ABC-AF2084a
Hersteller	Abcepta
Menge	100 ug
Kategorie	Antibodies Primary Antibodies
Typ	Antibody Primary
Applikationen	WB, ELISA
Specific against	other
Host	Goat
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Similar products	TXNRD1, cytoplasmic, TR, GRIM-12, KM-102-derived reductase-like factor, Thioredoxin reductase 1, Gene associated with retinoic and interferon-induced mortality 12 protein, Gene associated with retinoic and IFN-induced mortality 12 protein, Thioredoxin reductase TR1, GRIM12, KDRF, 1.8.1.9
Lieferbar
Primary Accession	Q16881
Antigen Type	Synthetic Peptide
Application	WB, E
Bio Background	This gene encodes a member of the family of pyridine nucleotide oxidoreductases. This protein reduces thioredoxins as well as other substrates, and plays a role in selenium metabolism and protection against oxidative stress. The functional enzyme is thought to be a homodimer which uses FAD as a cofactor. Each subunit contains a selenocysteine (Sec) residue which is required for catalytic activity. The selenocysteine is encoded by the UGA codon that normally signals translation termination. The 3' UTR of selenocysteine-containing genes have a common stem-loop structure, the sec insertion sequence (SECIS), that is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. Alternative splicing results in several transcript variants encoding the same or different isoforms.
Bio References	Mammalian thioredoxin reductase 1: roles in redox homoeostasis and characterization of cellular targets. Turanov AA, et al. Biochem J, 2010 Sep 1. PMID 20536427. Thioredoxin reductase-1 mediates curcumin-induced radiosensitization of squamous carcinoma cells. Javvadi P, et al. Cancer Res, 2010 Mar 1. PMID 20160040. Low 8-oxo-7, 8-dihydro-2'-deoxyguanosine levels and influence of genetic background in an Andean population exposed to high levels of arsenic. Engstr枚m KS, et al. Mutat Res, 2010 Jan 5. PMID 19896490. Inhibition of thioredoxin reductase 1 by caveolin 1 promotes stress-induced premature senescence. Volonte D, et al. EMBO Rep, 2009 Dec. PMID 19820694. High levels of thioredoxin reductase 1 modulate drug-specific cytotoxic efficacy. Eriksson SE, et al. Free Radic Biol Med, 2009 Dec 1. PMID 19766715.
Clonality	Polyclonal
Gene ID	7296
Gene Name	TXNRD1
Subtitle	Peptide-affinity purified goat antibody
Reactivity	H
Legend image 1	AF2084a staining (0.1 µg/ml) of Human Placenta lysate (RIPA buffer, 35 µg total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence.
Type image 1	WB
Other Accession	NP_001087240; 7296;
Predicted	Pig
Concentration (mg/ml)	100ug/200ul

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Arbeitsanleitung (Data Sheet) anfordern

ABC-AF2084a-datasheet.pdf

Sicherheitsdatenblatt anfordern

Einfache Bestellung Periodische Bestellung

Menge: 100 ug

lieferbar

Lieferung vsl. bis 04.09.2025