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CD106 / VCAM1 (Activated Endothelial Cell Marker) Antibody - With BSA and Azide

ArtNr ABC-AH12505-U0020
Hersteller Abcepta
Menge 20 ug
Kategorie
Typ Antibody Primary
Applikationen FC, IF, IHC
Clon VCAM1/843
Specific against other
Host Mouse
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Similar products VCAM-1, VCAM1, L1CAM, Vascular cell adhesion protein 1, INCAM-100, V-CAM 1, CD106
Lieferbar
Primary Accession
P19320
Application
IHC, IF, FC
Bio Background
Recognizes a protein of 110kDa, identified as CD106 (also known as vascular cell adhesion molecule-1 (VCAM-1) and INCAM-100). CD106 is a member of the Ig superfamily of adhesion molecules and is expressed at high levels on cytokine stimulated vascular endothelial cells, and at minimal levels on un-stimulated endothelial cells. It is also present on follicular and inter-follicular dendritic cells of lymph nodes, myoblasts, and some macrophages. CD106 serves as a ligand for leukocyte integrin (VLA-4 or CD49d/CD29) and mediates cell adhesion of leukocytes to activated endothelium. It plays a role in various immunological and inflammatory responses.
Bio References
Vermot-Desroches C et al. Heterogeneity of antigen expression among human umbilical cord vascular endothelial cells: identification of cell subsets by co-expression of haemopoietic antigens. Immunol Lett 1995, 48(1):1-9 | Rice GE et al. Vascular and nonvascular expression of INCAM-110. A target for mononuclear leukocyte adhesion in normal and inflamed human tissues. Am J Pathol 1991, 138(2):385-393 | Huang MJ et al. Expression of vascular cell adhesion molecule-1 by follicular dendritic cells. Leuk Lymphoma 1995, 18(3-4):259-264
Clonality
Monoclonal
Gene ID
7412
Gene Name
VCAM1
Subtitle
Mouse Monoclonal Antibody [Clone VCAM1/843 ]
Reactivity
H
Legend image 1
Formalin-fixed, paraffin-embedded human Tonsil stained with CD106 Monoclonal Antibody (VCAM1/843).
Type image 1
IHC
Other Accession
7412, 109225
Clone: VCAM1/843

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 20 ug
Lieferbar: In stock
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