Vergleich

Anti-CD11c (Dendritic Cell Marker) Antibody

ArtNr ABC-AH13329-U0020
Hersteller Abcepta
Menge 20 ug
Kategorie
Typ Antibody Primary
Applikationen FC, IF, IHC-P
Clon ITGAX/1284
Specific against other
Host Mouse
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Similar products alpha X (antigen CD11C (p150), CD11 antigen-like family member C; Complement component 3 receptor 4 subunit; Integrin alpha-X; integrin, alpha polypeptide); Leu M5 alpha subunit; Leukocyte adhesion glycoprotein p150 95 alpha chain; Myeloid membrane antigen alpha subunit; p150/95
Lieferbar
Primary Accession
P20702
Antigen Type
Recombinant protein
Application
IHC-P, IF, FC
Bio Background
Recognizes a protein of 145kDa, identified as CD11c. CD11c (ITGAX), a member of the leukointegrin family, shares the same beta subunit with other members of the leukocyte adhesion molecule family, which includes CD11a (LFA-1), CD11b (MAC-1) and CD11d (ITGAD), but has a unique alpha chain. CD11c has been shown to play a role in phagocytosis, cell migration, and cytokine production by monocytes/macrophages as well as induction of T-cell proliferation by Langerhans cells. CD11c is expressed prominently on the plasma membranes of monocytes, tissue macrophages, NK cells, and most dendritic cells (DCs). A lower level of expression is also observed on neutrophils as a result of its high level of expression on most DCs. An antibody to CD11c may aid in identification of lesions with histiocytic origin. It may also been used as a marker for hairy cell leukemia in paraffin-embedded tissues.
Clonality
Monoclonal
Gene ID
3687
Gene Name
ITGAX
Subtitle
Mouse Monoclonal Antibody
Reactivity
H
Legend image 1
Formalin-fixed, paraffin-embedded human Tonsil stained with CD11c Monoclonal Antibody (ITGAX/1284).
Type image 1
IHC-P
Other Accession
248472
Clone: ITGAX/1284

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Menge: 20 ug
Lieferbar: In stock
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