Hersteller |
Abcepta
|
Kategorie |
|
Typ |
Antibody Primary |
Specific against |
other |
Applikationen |
WB, ELISA, IHC-P |
Menge |
50 ug |
Host |
Goat |
ArtNr |
ABC-ALS13110 |
eClass 6.1 |
32160702 |
eClass 9.0 |
32160702 |
Lieferbar |
|
Primary Accession |
P17096 |
Antigen Type |
Synthetic peptide |
Application |
WB, IHC-P, E |
Bio Background |
HMG-I/Y bind preferentially to the minor groove of A+T rich regions in double-stranded DNA. It is suggested that these proteins could function in nucleosome phasing and in the 3'-end processing of mRNA transcripts. They are also involved in the transcription regulation of genes containing, or in close proximity to A+T-rich regions. |
Bio References |
Eckner R., et al.Nucleic Acids Res. 17:5947-5959(1989).Johnson K.R., et al.Mol. Cell. Biol. 9:2114-2123(1989).Friedmann M., et al.Nucleic Acids Res. 21:4259-4267(1993).Nagpal S., et al.J. Biol. Chem. 274:22563-22568(1999).Mungall A.J., et al.Nature 425:805-811(2003). |
Clonality |
Polyclonal |
Gene ID |
3159 |
Gene Name |
HMGA1 |
Subtitle |
Goat Polyclonal Antibody |
Reactivity |
H, M, Rat, Rb, Ha, Pr, Pig, Hs, Dog |
Legend image 1 |
Anti-HMGA1 antibody IHC of human placenta. |
Type image 1 |
IHC |
Legend image 2 |
Anti-HMGA1 antibody IHC of human skin. |
Type image 2 |
IHC |
Legend image 3 |
Staining (0.5 ug/ml) of Human Pancreas lysate (35 ug protein in RIPA buffer) with (B) and... |
Type image 3 |
WB |
Calculated MW |
11676 |
Target/Specificity |
Human HMGA1. This antibody is expected to recognize reported isoforms a (NP_665906.1, NP_665908.1, NP_665911.1) and b (NP_002122.1, NP_665910.1, NP_665912.1). This antibody is not expected to cross-react with HMGA2. |
Purification |
Immunoaffinity purified |
Concentration (mg/ml) |
0.5 mg/ml |
Reconstitution & Storage |
Store at -20°C. Minimize freezing and thawing. |
Dilution |
ELISA (1:16000), IHC-P (3.75 µg/ml), WB (0.5-1 µg/ml) |
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