Manufacturer |
Abcepta
|
Category |
|
Type |
Antibody Primary |
Specific against |
other |
Applications |
WB, ELISA, IHC-P |
Amount |
50 ug |
Host |
Goat |
Item no. |
ABC-ALS13110 |
eClass 6.1 |
32160702 |
eClass 9.0 |
32160702 |
Available |
|
Primary Accession |
P17096 |
Antigen Type |
Synthetic peptide |
Application |
WB, IHC-P, E |
Bio Background |
HMG-I/Y bind preferentially to the minor groove of A+T rich regions in double-stranded DNA. It is suggested that these proteins could function in nucleosome phasing and in the 3'-end processing of mRNA transcripts. They are also involved in the transcription regulation of genes containing, or in close proximity to A+T-rich regions. |
Bio References |
Eckner R., et al.Nucleic Acids Res. 17:5947-5959(1989).Johnson K.R., et al.Mol. Cell. Biol. 9:2114-2123(1989).Friedmann M., et al.Nucleic Acids Res. 21:4259-4267(1993).Nagpal S., et al.J. Biol. Chem. 274:22563-22568(1999).Mungall A.J., et al.Nature 425:805-811(2003). |
Clonality |
Polyclonal |
Gene ID |
3159 |
Gene Name |
HMGA1 |
Subtitle |
Goat Polyclonal Antibody |
Reactivity |
H, M, Rat, Rb, Ha, Pr, Pig, Hs, Dog |
Legend image 1 |
Anti-HMGA1 antibody IHC of human placenta. |
Type image 1 |
IHC |
Legend image 2 |
Anti-HMGA1 antibody IHC of human skin. |
Type image 2 |
IHC |
Legend image 3 |
Staining (0.5 ug/ml) of Human Pancreas lysate (35 ug protein in RIPA buffer) with (B) and... |
Type image 3 |
WB |
Calculated MW |
11676 |
Target/Specificity |
Human HMGA1. This antibody is expected to recognize reported isoforms a (NP_665906.1, NP_665908.1, NP_665911.1) and b (NP_002122.1, NP_665910.1, NP_665912.1). This antibody is not expected to cross-react with HMGA2. |
Purification |
Immunoaffinity purified |
Concentration (mg/ml) |
0.5 mg/ml |
Reconstitution & Storage |
Store at -20°C. Minimize freezing and thawing. |
Dilution |
ELISA (1:16000), IHC-P (3.75 µg/ml), WB (0.5-1 µg/ml) |
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.