Vergleich

BMP4 Antibody

ArtNr ABC-AM1872b-ev-80ul
Hersteller Abcepta
Menge 80 ul
Kategorie
Typ Antibody Monoclonal
Applikationen Western Blot
Clon RB50568
Specific against other
Host Mouse
Isotype IgM kappa
ECLASS 10.1 42030590
ECLASS 11.0 42030590
UNSPSC 12352203
Alias Bone morphogenetic protein 4, BMP-4, Bone morphogenetic protein 2B, BMP-2B, BMP4, BMP2B, DVR4
Lieferbar
Primary Accession
P12644
Other Accession
NP_570911.2; NP_001193.2
Antigen Type
Recombinant Protein
Bio Background
The protein encoded by this gene is a member of the bone
morphogenetic protein family which is part of the transforming
growth factor-beta superfamily. The superfamily includes large
families of growth and differentiation factors. Bone morphogenetic
proteins were originally identified by an ability of demineralized
bone extract to induce endochondral osteogenesis in vivo in an
extraskeletal site. This particular family member plays an
important role in the onset of endochondral bone formation in
humans, and a reduction in expression has been associated with a
variety of bone diseases, including the heritable disorder
Fibrodysplasia Ossificans Progressiva. Alternative splicing in the
5' untranslated region of this gene has been described and three
variants are described, all encoding an identical protein.
Bio References
Kupfer, S.S., et al. Gastroenterology 139(5):1677-1685(2010)
Kim, H.N., et al. J. Hum. Genet. 55(10):681-690(2010)
Nikopensius, T., et al. Birth Defects Res. Part A Clin. Mol. Teratol. 88(9):748-756(2010)
Jugessur, A., et al. PLoS ONE 5 (7), E11493 (2010) :
Johnatty, S.E., et al. PLoS Genet. 6 (7), E1001016 (2010) :
Gene ID
652
Gene Name
BMP4
Reactivity
H
Calculated MW
46555
Antigen Source
HUMAN
Target/Specificity
This BMP4 monoclonal antibody is generated from mouse immunized with BMP4 recombinant protein.
NCBI Accession
NP_001193.2; NP_570911.2; NP_570912.2

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