ACF Antibody (C-term)

NP_620310

Mammalian apolipoprotein B mRNA undergoes site-specific C
to U deamination, which is mediated by a multi-component enzyme
complex containing a minimal core composed of APOBEC-1 and a
complementation factor encoded by this gene. The gene product has
three non-identical RNA recognition motifs and belongs to the hnRNP
R family of RNA-binding proteins. It has been proposed that this
complementation factor functions as an RNA-binding subunit and
docks APOBEC-1 to deaminate the upstream cytidine. Studies suggest
that the protein may also be involved in other RNA editing or RNA
processing events.

29974

H

394-423

This ACF antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 394-423 amino acids from the C-terminal region of human ACF.