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PCDH1 Antibody (N-term)

PCDH1 Antibody (N-term)

ArtNr	ABC-AP12019a-ev
Hersteller	Abcepta
Menge	80 ul
Kategorie	Antibodies Primary Antibodies
Typ	Antibody Primary
Format	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Applikationen	WB, IF, IHC-P
Specific against	other
Host	Rabbit
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Similar products	PCDH1, Protocadherin-1, Cadherin-like protein 1, Protocadherin-42, PC42
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Primary Accession	Q08174
Antigen Type	Synthetic Peptide
Application	IF, WB, IHC-P
Bio Background	This gene belongs to the protocadherin subfamily within the cadherin superfamily. The encoded protein is a membrane protein found at cell-cell boundaries. It is involved in neural cell adhesion, suggesting a possible role in neuronal development. The protein includes an extracelllular region, containing 7 cadherin-like domains, a transmembrane region and a C-terminal cytoplasmic region. Cells expressing the protein showed cell aggregation activity. Alternative splicing occurs in this gene.
Bio References	Koppelman, G.H., et al. Am. J. Respir. Crit. Care Med. 180(10):929-935(2009) Rush, J., et al. Nat. Biotechnol. 23(1):94-101(2005) Ballif, B.A., et al. Mol. Cell Proteomics 3(11):1093-1101(2004) Ballif, B.A., et al. Mol. Cell Proteomics 3(11):1093-1101(2004) Colland, F., et al. Genome Res. 14(7):1324-1332(2004)
Clonality	Polyclonal
Clone/Animal Names	RB31671
Gene ID	5097
Gene Name	PCDH1
Subtitle	Affinity Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	H
Legend image 1	Confocal immunofluorescent analysis of PCDH1 Antibody (N-term)(Cat#AP12019a) with U-251MG cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). DAPI was used to stain the cell nuclear (blue).
Type image 1	IF
Dilution image 1	1:10~50
Legend image 2	PCDH1 Antibody (N-term) (Cat. #AP12019a) western blot analysis in MDA-MB453, ZR-75-1 cell line lysates (35ug/lane).This demonstrates the PCDH1 antibody detected the PCDH1 protein (arrow).
Type image 2	WB
Dilution image 2	1:1000
Legend image 3	PCDH1 Antibody (N-term) (Cat. #AP12019a)immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of PCDH1 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.
Type image 3	IHC-P
Dilution image 3	1:10~50
Other Accession	NP_115796.2
Isotype	Rabbit Ig
Calculated MW	114743
Antigen Region	179-206
Antigen Source	HUMAN
Target/Specificity	This PCDH1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 179-206 amino acids from the N-terminal region of human PCDH1.
NCBI Accession	NP_001265542.1; NP_001265544.1; NP_002578.2; NP_115796.2

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Menge: 80 ul

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