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PCDH1 Antibody (N-term)

PCDH1 Antibody (N-term)

Item no.	ABC-AP12019a-ev
Manufacturer	Abcepta
Amount	80 ul
Category	Antibodies Primary Antibodies
Type	Antibody Primary
Format	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Applications	WB, IF, IHC-P
Specific against	other
Host	Rabbit
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Similar products	PCDH1, Protocadherin-1, Cadherin-like protein 1, Protocadherin-42, PC42
Available
Primary Accession	Q08174
Antigen Type	Synthetic Peptide
Application	IF, WB, IHC-P
Bio Background	This gene belongs to the protocadherin subfamily within the cadherin superfamily. The encoded protein is a membrane protein found at cell-cell boundaries. It is involved in neural cell adhesion, suggesting a possible role in neuronal development. The protein includes an extracelllular region, containing 7 cadherin-like domains, a transmembrane region and a C-terminal cytoplasmic region. Cells expressing the protein showed cell aggregation activity. Alternative splicing occurs in this gene.
Bio References	Koppelman, G.H., et al. Am. J. Respir. Crit. Care Med. 180(10):929-935(2009) Rush, J., et al. Nat. Biotechnol. 23(1):94-101(2005) Ballif, B.A., et al. Mol. Cell Proteomics 3(11):1093-1101(2004) Ballif, B.A., et al. Mol. Cell Proteomics 3(11):1093-1101(2004) Colland, F., et al. Genome Res. 14(7):1324-1332(2004)
Clonality	Polyclonal
Clone/Animal Names	RB31671
Gene ID	5097
Gene Name	PCDH1
Subtitle	Affinity Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	H
Legend image 1	Confocal immunofluorescent analysis of PCDH1 Antibody (N-term)(Cat#AP12019a) with U-251MG cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). DAPI was used to stain the cell nuclear (blue).
Type image 1	IF
Dilution image 1	1:10~50
Legend image 2	PCDH1 Antibody (N-term) (Cat. #AP12019a) western blot analysis in MDA-MB453, ZR-75-1 cell line lysates (35ug/lane).This demonstrates the PCDH1 antibody detected the PCDH1 protein (arrow).
Type image 2	WB
Dilution image 2	1:1000
Legend image 3	PCDH1 Antibody (N-term) (Cat. #AP12019a)immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of PCDH1 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.
Type image 3	IHC-P
Dilution image 3	1:10~50
Other Accession	NP_115796.2
Isotype	Rabbit Ig
Calculated MW	114743
Antigen Region	179-206
Antigen Source	HUMAN
Target/Specificity	This PCDH1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 179-206 amino acids from the N-terminal region of human PCDH1.
NCBI Accession	NP_001265542.1; NP_001265544.1; NP_002578.2; NP_115796.2

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 80 ul

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Delivery expected until 10/2/2025

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