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FBXO15 Antibody (N-term)

FBXO15 Antibody (N-term)

ArtNr	ABC-AP12418a-ev
Hersteller	Abcepta
Menge	80 ul
Kategorie	Antibodies Primary Antibodies
Typ	Antibody Primary
Format	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Applikationen	WB, IHC-P
Specific against	other
Host	Rabbit
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Similar products	FBXO15, FBX15, F-box only protein 15
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Primary Accession	Q8NCQ5
Antigen Type	Synthetic Peptide
Application	IHC-P, WB
Bio Background	Members of the F-box protein family, such as FBXO15, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1; MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004 [PubMed 15520277]).[supplied by OMIM].
Bio References	Lamesch, P., et al. Genomics 89(3):307-315(2007) Jin, J., et al. Genes Dev. 18(21):2573-2580(2004) Tokuzawa, Y., et al. Mol. Cell. Biol. 23(8):2699-2708(2003) Winston, J.T., et al. Curr. Biol. 9(20):1180-1182(1999)
Clonality	Polyclonal
Clone/Animal Names	RB20739
Gene ID	201456
Gene Name	FBXO15
Subtitle	Affinity Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	H
Legend image 1	FBXO15 Antibody (N-term) (Cat. #AP12418a) western blot analysis in NCI-H292 cell line lysates (35ug/lane).This demonstrates the FBXO15 antibody detected the FBXO15 protein (arrow).
Type image 1	WB
Dilution image 1	1:1000
Legend image 2	FBXO15 Antibody (N-term) (Cat. #AP12418a)immunohistochemistry analysis in formalin fixed and paraffin embedded human testis tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of FBXO15 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.
Type image 2	IHC-P
Dilution image 2	1:10~50
Other Accession	Q9GKV7; NP_689889.1
Predicted	Pr
Isotype	Rabbit Ig
Calculated MW	57258
Antigen Region	130-158
Antigen Source	HUMAN
Target/Specificity	This FBXO15 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 130-158 amino acids from the N-terminal region of human FBXO15.
NCBI Accession	NP_001136430.1; NP_689889.1

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