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DPYS Antibody (C-term)

DPYS Antibody (C-term)

ArtNr	ABC-AP13434b-ev
Hersteller	Abcepta
Menge	80 ul
Kategorie	Antibodies Primary Antibodies
Typ	Antibody Primary
Format	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Applikationen	WB, IHC-P
Specific against	other
Host	Rabbit
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Similar products	DPYS, Dihydropyrimidinase, Dihydropyrimidine amidohydrolase, Hydantoinase, DHP, DHPase
Lieferbar
Primary Accession	Q14117
Antigen Type	Synthetic Peptide
Application	IHC-P, WB
Bio Background	Dihydropyrimidinase catalyzes the conversion of 5, 6-dihydrouracil to 3-ureidopropionate in pyrimidine metabolism. Dihydropyrimidinase is expressed at a high level in liver and kidney as a major 2.5-kb transcript and a minor 3.8-kb transcript. Defects in the DPYS gene are linked to dihydropyrimidinuria.
Bio References	Kim, H.Y., et al. BMB Rep 43(8):547-553(2010) van Kuilenburg, A.B., et al. Biochim. Biophys. Acta 1802 (7-8), 639-648 (2010) : Fidlerova, J., et al. Cancer Chemother. Pharmacol. 65(4):661-669(2010) Thomas, H.R., et al. Pharmacogenet. Genomics 18(1):25-35(2008) Thomas, H.R., et al. Pharmacogenet. Genomics 17(11):973-987(2007)
Clonality	Polyclonal
Clone/Animal Names	RB21564
Gene ID	1807
Gene Name	DPYS
Subtitle	Affinity Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	H
Legend image 1	DPYS Antibody (C-term) (Cat. #AP13434b) western blot analysis in Jurkat, K562 cell line lysates (35ug/lane).This demonstrates the DPYS antibody detected the DPYS protein (arrow).
Type image 1	WB
Dilution image 1	1:1000
Legend image 2	DPYS Antibody (C-term) (Cat. #AP13434b)immunohistochemistry analysis in formalin fixed and paraffin embedded human kidney tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of DPYS Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.
Type image 2	IHC-P
Dilution image 2	1:10~50
Other Accession	NP_001376.1
Isotype	Rabbit Ig
Calculated MW	56630
Antigen Region	454-482
Antigen Source	HUMAN
Target/Specificity	This DPYS antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 454-482 amino acids from the C-terminal region of human DPYS.
NCBI Accession	NP_001376.1

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Menge: 80 ul

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