« Zurück
Startseite /
MARCH1 Antibody (Center)

MARCH1 Antibody (Center)

ArtNr	ABC-AP14345c
Hersteller	Abcepta
Menge	400 ul
Kategorie	Antibodies Primary Antibodies
Typ	Antibody Primary
Format	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Applikationen	WB
Specific against	other
Host	Rabbit
Isotype	Ig
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Similar products	MARCH1, RNF171, E3 ubiquitin-protein ligase MARCH1, Membrane-associated RING finger protein 1, Membrane-associated RING-CH protein I, RING finger protein 171, MARCH-I, 632-
Lieferbar
Primary Accession	Q8TCQ1
Antigen Type	Synthetic Peptide
Application	WB
Bio Background	MARCH1 is a member of the MARCH family of membrane-bound E3 ubiquitin ligases (EC 6.3.2.19). MARCH proteins add ubiquitin (see MIM 191339) to target lysines in substrate proteins, thereby signaling their vesicular transport between membrane compartments. MARCH1 downregulates the surface expression of major histocompatibility complex (MHC) class II molecules (see MIM 142880) and other glycoproteins by directing them to the late endosomal/lysosomal compartment (Bartee et al., 2004 [PubMed 14722266]; Thibodeau et al., 2008 [PubMed 18389477]; De Gassart et al., 2008 [PubMed 18305173]).
Bio References	Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) : Thibodeau, J., et al. Eur. J. Immunol. 38(5):1225-1230(2008) De Gassart, A., et al. Proc. Natl. Acad. Sci. U.S.A. 105(9):3491-3496(2008) Bartee, E., et al. J. Virol. 78(3):1109-1120(2004)
Clonality	Polyclonal
Clone/Animal Names	RB33494
Gene ID	55016
Gene Name	MARCHF1 (HGNC:26077)
Subtitle	Affinity Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	M
Legend image 1	MARCH1 Antibody (Center) (Cat. #AP14345c) western blot analysis in mouse heart tissue lysates (35ug/lane).This demonstrates the MARCH1 antibody detected the MARCH1 protein (arrow).
Type image 1	WB
Dilution image 1	1:1000
Other Accession	Q6NZQ8; NP_060393.1; NP_001159845.1
Isotype	Rabbit Ig
Calculated MW	32308
Antigen Region	163-191
Antigen Source	HUMAN
Target/Specificity	This MARCH1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 163-191 amino acids from the Central region of human MARCH1.
NCBI Accession	NP_001159845.1; NP_060393.1

Hinweis: Die dargestellten Informationen und Dokumente (Bedienungsanleitung, Produktdatenblatt, Sicherheitsdatenblatt und Analysezertifikat) entsprechen unserem letzten Update und sollten lediglich der Orientierung dienen. Wir übernehmen keine Garantie für die Aktualität. Für spezifische Anforderungen bitten wir Sie, uns eine Anfrage zu stellen.

Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Arbeitsanleitung (Data Sheet) anfordern

ABC-AP14345c-datasheet.pdf

Sicherheitsdatenblatt anfordern

Einfache Bestellung Periodische Bestellung

Menge: 400 ul

lieferbar

Lieferung vsl. bis 02.10.2025

Express-Lieferung: 17 Tage sparen

Vergleichen

Auf den Wunschzettel

Angebot anfordern