Vergleich

METAP2 Antibody (N-term)

ArtNr ABC-AP14389a-ev
Hersteller Abcepta
Menge 80 ul
Kategorie
Typ Antibody Primary
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Applikationen WB
Specific against other
Host Rabbit
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Similar products Methionine aminopeptidase 2 {ECO:0000255|HAMAP-Rule:MF_03175}, MAP 2 {ECO:0000255|HAMAP-Rule:MF_03175}, MetAP 2 {ECO:0000255|HAMAP-Rule:MF_03175}, 341118 {ECO:0000255|HAMAP-Rule:MF_03175}, Initiation factor 2-associated 67 kDa glycoprotein {ECO:0000255|HAMAP-Rule:MF_03175}, p67 {ECO:0000255|HAMAP-Rule:MF_03175}, p67eIF2 {ECO:0000255|HAMAP-Rule:MF_03175}, Peptidase M {ECO:0000255|HAMAP-Rule:MF_03175}, METAP2 {ECO:0000255|HAMAP-Rule:MF_03175}
Lieferbar
Primary Accession
P50579
Antigen Type
Synthetic Peptide
Application
WB
Bio Background
This gene is a member of the methionyl aminopeptidase
family and encodes a protein that binds 2 cobalt or manganese ions.
This protein functions both by protecting the alpha subunit of
eukaryotic initiation factor 2 from inhibitory phosphorylation and
by removing the amino-terminal methionine residue from nascent
protein. Increased expression of this gene is associated with
various forms of cancer and the anti-cancer drugs fumagillin and
ovalicin inhibit the protein by irreversibly binding to its active
site. A pseudogene of this gene is located on chromosome 2.
Bio References
Xiao, Q., et al. Biochemistry 49(26):5588-5599(2010)
Wang, X., et al. PLoS ONE 5 (8), E11934 (2010) :
Selvakumar, P., et al. Mol. Cancer 8, 65 (2009) :
Warder, S.E., et al. J. Proteome Res. 7(11):4807-4820(2008)
Tucker, L.A., et al. Oncogene 27(28):3967-3976(2008)
Clonality
Polyclonal
Clone/Animal Names
RB34311
Gene ID
10988
Gene Name
METAP2 {ECO:0000255|HAMAP-Rule:MF_03175}
Subtitle
Affinity Purified Rabbit Polyclonal Antibody (Pab)
Reactivity
H
Legend image 1
METAP2 Antibody (N-term) (Cat. #AP14389a) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the METAP2 antibody detected the METAP2 protein (arrow).
Type image 1
WB
Dilution image 1
1:1000
Legend image 2
Western blot analysis of METAP2 (arrow) using rabbit polyclonal METAP2 Antibody (N-term) (Cat. #AP14389a). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the METAP2 gene.
Type image 2
WB
Dilution image 2
1:1000
Other Accession
NP_006829.1
Isotype
Rabbit Ig
Calculated MW
52892
Antigen Region
33-61
Antigen Source
HUMAN
Target/Specificity
This METAP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 33-61 amino acids from the N-terminal region of human METAP2.
NCBI Accession
NP_006829.1

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 80 ul
Lieferbar: In stock
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