TRIM25 Antibody (Center)

Synthetic Peptide

The protein encoded by this gene is a member of the
tripartite motif (TRIM) family. The TRIM motif includes three
zinc-binding domains, a RING, a B-box type 1 and a B-box type 2,
and a coiled-coil region. The protein localizes to the cytoplasm.
The presence of potential DNA-binding and
dimerization-transactivation domains suggests that this protein may
act as a transcription factor, similar to several other members of
the TRIM family. Expression of the gene is upregulated in response
to estrogen, and it is thought to mediate estrogen actions in
breast cancer as a primary response gene.

Polyclonal

7706

Affinity Purified Rabbit Polyclonal Antibody (Pab)

TRIM25 Antibody (Center) (Cat. #AP16857c) western blot analysis in MDA-MB231 cell line lysates (35ug/lane).This demonstrates the TRIM25 antibody detected the TRIM25 protein (arrow).

1:1000

Rabbit Ig

277-306

This TRIM25 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 277-306 amino acids from the Central region of human TRIM25.