Vergleich

Chemokine Receptor D6 (CCBP2) Antibody (C-term)

ArtNr ABC-AP2012b-ev-80ul
Hersteller Abcepta
Menge 80 ul
Kategorie
Typ Antibody Polyclonal
Applikationen Western Blot, Immunohistochemistry
Specific against other
Host Rabbit
Isotype Ig
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias Atypical chemokine receptor 2, C-C chemokine receptor D6, Chemokine receptor CCR-10, Chemokine receptor CCR-9, Chemokine-binding protein 2, Chemokine-binding protein D6, ACKR2, CCBP2, CCR10, CMKBR9, D6
Lieferbar
Primary Accession
O00590
Other Accession
NP_001287
Antigen Type
Synthetic Peptide
Bio Background
CCBP2 is a beta chemokine receptor, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. Chemokines and their receptor-mediated signal transduction are critical for the recruitment of effector immune cells to the inflammation site. This gene is expressed in a range of tissues and hemopoietic cells. The expression of this receptor in lymphatic endothelial cells and overexpression in vascular tumors suggested its function in chemokine-driven recirculation of leukocytes and possible chemokine effects on the development and growth of vascular tumors. This receptor appears to bind the majority of beta-chemokine family members; however, its specific function remains unknown. This gene is mapped to chromosome 3p21.3, a region that includes a cluster of chemokine receptor genes.
Bio References
Kunkel, E.J., et al., J. Clin. Invest. 111(7):1001-1010 (2003).
Fra, A.M., et al., J. Immunol. 170(5):2279-2282 (2003).
Soler, D., et al., Blood 101(5):1677-1682 (2003).
Nibbs, R.J., et al., Am. J. Pathol. 158(3):867-877 (2001).
Bonini, J.A., et al., DNA Cell Biol. 16(10):1249-1256 (1997).
Gene ID
1238
Gene Name
ACKR2
Reactivity
H, M
Calculated MW
43443
Antigen Region
298-328
Antigen Source
HUMAN
Target/Specificity
This Chemokine Receptor D6 (CCBP2) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 298-328 amino acids from the C-terminal region of human Chemokine Receptor D6 (CCBP2).
NCBI Accession
NP_001287.2

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