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PIK3R1/2 Antibody (Center)

PIK3R1/2 Antibody (Center)

ArtNr	ABC-AP20768c-ev
Hersteller	Abcepta
Menge	80 ul
Kategorie	Antibodies Primary Antibodies
Typ	Antibody Primary
Format	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Applikationen	WB
Specific against	other
Host	Rabbit
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Similar products	PIK3R1, Phosphatidylinositol 3-kinase regulatory subunit alpha, Phosphatidylinositol 3-kinase 85 kDa regulatory subunit alpha, GRB1, PI3-kinase regulatory subunit alpha, PI3K regulatory subunit alpha, PtdIns-3-kinase regulatory subunit alpha, PI3-kinase subunit p85-alpha, PtdIns-3-kinase regulatory subunit p85-alpha
Lieferbar
Primary Accession	P27986
Application	WB
Bio Background	Binds to activated (phosphorylated) protein-Tyr kinases, through its SH2 domain, and acts as an adapter, mediating the association of the p110 catalytic unit to the plasma membrane. Necessary for the insulin-stimulated increase in glucose uptake and glycogen synthesis in insulin-sensitive tissues. Plays an important role in signaling in response to FGFR1, FGFR2, FGFR3, FGFR4, KITLG/SCF, KIT, PDGFRA and PDGFRB. Likewise, plays a role in ITGB2 signaling.
Bio References	Skolnik E.Y., et al.Cell 65:83-90(1991). Antonetti D.A., et al.Mol. Cell. Biol. 16:2195-2203(1996). Udelhoven M., et al.Submitted (JUN-2000) to the EMBL/GenBank/DDBJ databases. Ota T., et al.Nat. Genet. 36:40-45(2004). Totoki Y., et al.Submitted (APR-2005) to the EMBL/GenBank/DDBJ databases.
Clonality	Polyclonal
Clone/Animal Names	RB43844
Gene ID	5295
Gene Name	PIK3R1
Subtitle	Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	H, Rat
Legend image 1	Western blot analysis of lysates from U-937, Jurkat, C6 cell line (from left to right), using PIK3R1/2 Antibody (Center)(Cat. #AP20768c). AP20768c was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:5000 dilution was used as the secondary antibody. Lysates at 35ug per lane.
Type image 1	WB
Dilution image 1	1:1000
Other Accession	O00459; P23726; Q63787; P26450; P23727; Q8UUU2
Predicted	X, B, M
Isotype	Rabbit Ig
Calculated MW	83598
Antigen Source	HUMAN
Target/Specificity	This PIK3R1/2 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 337-370 amino acids from the Central region of human PIK3R1/2.

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Menge: 80 ul

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