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CBX7 Antibody (C-term)

CBX7 Antibody (C-term)

ArtNr	ABC-AP21163a
Hersteller	Abcepta
Menge	400 ul
Kategorie	Antibodies Primary Antibodies
Typ	Antibody Primary
Format	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Applikationen	WB
Specific against	other
Host	Rabbit
Isotype	Ig
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Similar products	CBX7, Chromobox protein homolog 7
Lieferbar
Primary Accession	O95931
Application	WB
Bio Background	Component of a Polycomb group (PcG) multiprotein PRC1- like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. Promotes histone H3 trimethylation at 'Lys-9' (H3K9me3). Binds to trimethylated lysine residues in histones, and possibly also other proteins. Regulator of cellular lifespan by maintaining the repression of CDKN2A, but not by inducing telomerase activity.
Bio References	Dunham I., et al.Nature 402:489-495(1999). Gil J., et al.Nat. Cell Biol. 6:67-72(2004). Bezsonova I., et al.Biochemistry 48:10542-10548(2009). Maertens G.N., et al.PLoS ONE 4:E6380-E6380(2009). Li Q., et al.PLoS ONE 5:E13732-E13732(2010).
Clonality	polyclonal
Clone/Animal Names	RB51547
Gene ID	23492
Gene Name	CBX7
Subtitle	Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	H
Legend image 1	Anti-CBX7 Antibody (C-term) at 1:1000 dilution + HepG2 whole cell lysates Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution Predicted band size : 28 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
Type image 1	WB
Dilution image 1	1:1000
Legend image 2	Anti-CBX7 Antibody (C-term) at 1:500 dilution + SK-N-MC whole cell lysates Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution Predicted band size : 28 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
Type image 2	WB
Dilution image 2	1:500
Isotype	Rabbit Ig
Calculated MW	28341
Antigen Source	HUMAN
Target/Specificity	This CBX7 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 168-201 amino acids from the C-terminal region of human CBX7.

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ABC-AP21163a-datasheet.pdf

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Menge: 400 ul

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Lieferung vsl. bis 04.09.2025