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Phospho-HER4(Y1162) Antibody

Phospho-HER4(Y1162) Antibody

ArtNr	ABC-AP3122a
Hersteller	Abcepta
Menge	400 ul
Kategorie	Antibodies Primary Antibodies
Typ	Antibody Primary
Format	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Applikationen	WB, IF, IHC-P
Specific against	other
Host	Rabbit
Isotype	Ig
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Similar products	ERBB4, HER4, Receptor tyrosine-protein kinase erbB-4, Proto-oncogene-like protein c-ErbB-4, Tyrosine kinase-type cell surface receptor HER4, p180erbB4, ERBB4 intracellular domain, s80HER4, 4ICD, E4ICD
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Primary Accession	Q15303
Antigen Type	Synthetic Peptide
Application	IF, WB, IHC-P
Bio Background	HER4/ERBB4 is a member of the type I receptor tyrosine kinase subfamily that includes EGFR, ERBB2 and ERBB3. It is a receptor for NDF/heregulin.
Bio References	Tanimura, K., et al., Eur. J. Endocrinol. 151(1):93-101 (2004). Hughes, D.P., et al., Cancer Res. 64(6):2047-2053 (2004). Cheng, Q.C., et al., J. Biol. Chem. 278(40):38421-38427 (2003). Chaudhury, A.R., et al., J. Neuropathol. Exp. Neurol. 62(1):42-54 (2003). Komuro, A., et al., J. Biol. Chem. 278(35):33334-33341 (2003).
Clonality	Polyclonal
Clone/Animal Names	RB5687
Gene ID	2066
Gene Name	ERBB4
Subtitle	Affinity Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	H
Legend image 1	Confocal immunofluorescent analysis of Phospho-HER4-Y1162 Antibody(Cat#AP3122a) with MCF-7 cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). Actin filaments have been labeled with Alexa Fluor 555 phalloidin (red).DAPI was used to stain the cell nuclear (blue).
Type image 1	IF
Dilution image 1	1:10~50
Legend image 2	Western blot analysis of lysates from A431 cell line, untreated or treated with EGF, 100ng/ml, using (Cat. #AP3122a)(upper) or Tubulin (lower).
Type image 2	WB
Dilution image 2	1:500
Legend image 3	AP3122a staining HER4(Y1162) in human heart tissue sections by Immunohistochemistry (IHC-P - paraformaldehyde-fixed, paraffin-embedded sections). Tissue was fixed with formaldehyde and blocked with 3% BSA for 0. 5 hour at room temperature; antigen retrieval was by heat mediation with a citrate buffer (pH6). Samples were incubated with primary antibody (1/25) for 1 hours at 37°C. A undiluted biotinylated goat polyvalent antibody was used as the secondary antibody.
Type image 3	IHC-P
Dilution image 3	1:25
Other Accession	Q62956; Q61527
Predicted	M, Rat
Isotype	Rabbit Ig
Calculated MW	146808
Antigen Source	HUMAN
Target/Specificity	This HER4 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding Y1162 of human HER4.
NCBI Accession	NP_001036064.1; NP_005226.1

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ABC-AP3122a-datasheet.pdf

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Menge: 400 ul

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Lieferung vsl. bis 04.09.2025

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