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Phospho-CRK(S41) Antibody

Phospho-CRK(S41) Antibody

ArtNr	ABC-AP3304a
Hersteller	Abcepta
Menge	400 ul
Kategorie	Antibodies Primary Antibodies Dot Blot
Typ	Antibody Polyclonal
Applikationen	Dot
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
Citations	Bougneres, L., et al., J. Cell Biol. 166(2):225-235 (2004). Stoletov, K.V., et al., Exp. Cell Res. 295(1):258-268 (2004). Miller, C.T., et al., Oncogene 22(39):7950-7957 (2003). Sun, J., et al., J. Biol. Chem. 278(35):32794-32800 (2003). Zhang, X.A., et al., J. Biol. Chem. 278(29):27319-27328 (2003).
NCBI	NP_005197.3,NP_058431.2
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Adapter molecule crk,Proto-oncogene c-Crk,p38,CRK
Similar products	CRK, p38, Adapter molecule crk, Proto-oncogene c-Crk
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Manufacturer - Category	Primary Antibodies; Antibody Collections; Cancer; Signal Transduction; Phospho Antibodies; Fc gamma R-mediated phagocytosis; Chemokine signaling
Manufacturer - Targets	This CRK Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S41 of human CRK.
Bio Background	CRK is a member of an adapter protein family that binds to several tyrosine-phosphorylated proteins. It has several SH2 and SH3 domains (src-homology domains) and is involved in several signaling pathways, recruiting cytoplasmic proteins in the vicinity of tyrosine kinase through SH2-phosphotyrosine interaction. The N-terminal SH2 domain of this protein functions as a positive regulator of transformation whereas the C-terminal SH3 domain functions as a negative regulator of transformation.
Clonality	Polyclonal
Polyclonal Antibody Additonal Information	RB17175
Gene Name	CRK
Subtitle	Affinity Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	H
Predicted Reactivity	M, Rat
Calculated Molecular Weight	33831
Antigen Source	HUMAN
Formulation	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Dilution	DB: 1:500
Antigen Type	Synthetic Peptide

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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ABC-AP3304a-datasheet.pdf

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Menge: 400 ul

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