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Phospho-MAP3K7(T187) Antibody

ArtNr ABC-AP3323a
Hersteller Abcepta
Menge 400 ul
Kategorie
Typ Antibody Polyclonal
Applikationen Dot
Specific against Human (Homo sapiens)
Host Rabbit
Isotype IgG
Citations Smit, L., et al., J. Biol. Chem. 279(17):17232-17240 (2004).
Ono, K., et al., Biochem. Biophys. Res. Commun. 307(2):332-337 (2003).
Sakurai, H., et al., J. Biol. Chem. 278(38):36916-36923 (2003).
Cheung, P.C., et al., EMBO J. 22(21):5793-5805 (2003).
Edlund, S., et al., Mol. Biol. Cell 14(2):529-544 (2003).
NCBI NP_003179.1,NP_663304.1,NP_663305.1,NP_663306.1
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias Mitogen-activated protein kinase kinase kinase 7,Transforming growth factor-beta-activated kinase 1,TGF-beta-activated kinase 1,MAP3K7,TAK1
Similar products TAK1, Mitogen-activated protein kinase kinase kinase 7, Transforming growth factor-beta-activated kinase 1, MAP3K7, TGF-beta-activated kinase 1
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Manufacturer - Category
Primary Antibodies; Antibody Collections; Cancer; Cardiovascular; Immunology; Signal Transduction; Phospho Antibodies; Anti-Wnt-Pathway (plus Lgr5) Antibodies; RIG-l-like Receptor; Toll receptor signaling; Toll-Like Receptor; Toll-Like receptor signaling; T cell receptor signaling; Inflammation mediated by chemokine and cytokine signaling; Interleukin signaling; Necroptosis; Stress response
Manufacturer - Targets
This MAP3K7 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding T187 of human MAP3K7.
Bio Background
MAP3K7 is a member of the serine/threonine protein kinase family. This kinase mediates the signaling transduction induced by TGF beta and morphogenetic protein (BMP), and controls a variety of cell functions including transcription regulation and apoptosis. In response to IL-1, this protein forms a kinase complex including TRAF6, MAP3K7P1/TAB1 and MAP3K7P2/TAB2; this complex is required for the activation of nuclear factor kappa B. This kinase can also activate MAPK8/JNK, MAP2K4/MKK4, and thus plays a role in the cell response to environmental stresses.
Clonality
Polyclonal
Polyclonal Antibody Additonal Information
RB11312
Gene Name
MAP3K7 {ECO:0000303|PubMed:28397838, ECO:0000312|HGNC:HGNC:6859}
Subtitle
Affinity Purified Rabbit Polyclonal Antibody (Pab)
Reactivity
H
Predicted Reactivity
B, M, Rat
Calculated Molecular Weight
67196
Antigen Source
HUMAN
Formulation
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Dilution
DB: 1:500
Antigen Type
Synthetic Peptide

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 400 ul
Lieferbar: In stock
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