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Phospho-MAP3K7(T187) Antibody

Phospho-MAP3K7(T187) Antibody

Item no.	ABC-AP3323a
Manufacturer	Abcepta
Amount	400 ul
Category	Antibodies Primary Antibodies Dot Blot
Type	Antibody Polyclonal
Applications	Dot
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
Citations	Smit, L., et al., J. Biol. Chem. 279(17):17232-17240 (2004). Ono, K., et al., Biochem. Biophys. Res. Commun. 307(2):332-337 (2003). Sakurai, H., et al., J. Biol. Chem. 278(38):36916-36923 (2003). Cheung, P.C., et al., EMBO J. 22(21):5793-5805 (2003). Edlund, S., et al., Mol. Biol. Cell 14(2):529-544 (2003).
NCBI	NP_003179.1,NP_663304.1,NP_663305.1,NP_663306.1
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Mitogen-activated protein kinase kinase kinase 7,Transforming growth factor-beta-activated kinase 1,TGF-beta-activated kinase 1,MAP3K7,TAK1
Similar products	TAK1, Mitogen-activated protein kinase kinase kinase 7, Transforming growth factor-beta-activated kinase 1, MAP3K7, TGF-beta-activated kinase 1
Available
Manufacturer - Category	Primary Antibodies; Antibody Collections; Cancer; Cardiovascular; Immunology; Signal Transduction; Phospho Antibodies; Anti-Wnt-Pathway (plus Lgr5) Antibodies; RIG-l-like Receptor; Toll receptor signaling; Toll-Like Receptor; Toll-Like receptor signaling; T cell receptor signaling; Inflammation mediated by chemokine and cytokine signaling; Interleukin signaling; Necroptosis; Stress response
Manufacturer - Targets	This MAP3K7 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding T187 of human MAP3K7.
Bio Background	MAP3K7 is a member of the serine/threonine protein kinase family. This kinase mediates the signaling transduction induced by TGF beta and morphogenetic protein (BMP), and controls a variety of cell functions including transcription regulation and apoptosis. In response to IL-1, this protein forms a kinase complex including TRAF6, MAP3K7P1/TAB1 and MAP3K7P2/TAB2; this complex is required for the activation of nuclear factor kappa B. This kinase can also activate MAPK8/JNK, MAP2K4/MKK4, and thus plays a role in the cell response to environmental stresses.
Clonality	Polyclonal
Polyclonal Antibody Additonal Information	RB11312
Gene Name	MAP3K7 {ECO:0000303\|PubMed:28397838, ECO:0000312\|HGNC:HGNC:6859}
Subtitle	Affinity Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	H
Predicted Reactivity	B, M, Rat
Calculated Molecular Weight	67196
Antigen Source	HUMAN
Formulation	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Dilution	DB: 1:500
Antigen Type	Synthetic Peptide

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 400 ul

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Delivery expected until 1/1/2026

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