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Phospho-EGFR(Y1016) Antibody

Phospho-EGFR(Y1016) Antibody

ArtNr	ABC-AP3507a-ev-80ul
Hersteller	Abcepta
Menge	80 ul
Kategorie	Oncology Neuroscience Neural Signaling Protein Aggregation, Clearance & Misfolding Antibodies Blastoma Carcinoma Glioma Hematology Leukemia Lymphoma Myeloma Melanoma Sarcoma Cell Biology Cell Culture Cytokines Adenocarcinoma Western Blot Primary Antibodies Astrocytoma Bladder Cancer Heart & Blood Cancer Dot Blot
Typ	Antibody Polyclonal
Applikationen	Western Blot, Dot blot
Specific against	other
Host	Rabbit
Isotype	Ig
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Epidermal growth factor receptor, Proto-oncogene c-ErbB-1, Receptor tyrosine-protein kinase erbB-1, EGFR, ERBB, ERBB1, HER1
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Primary Accession	P00533
Other Accession	Q01279
Antigen Type	Synthetic Peptide
Bio Background	Epidermal Growth factor receptor (EGFR) is the prototype member of the type 1 receptor tyrosine kinases. EGFR overexpression in tumors indicates poor prognosis and is observed in tumors of the head and neck, brain, bladder, stomach, breast, lung, endometrium, cervix, vulva, ovary, esophagus, stomach and in squamous cell carcinoma. EGFR is a receptor for EGF, but also for other members of the EGF family, including TGF-alpha, amphiregulin, betacellulin, heparin-binding EGF-like growth factor, GP30 and vaccinia virus growth factor. It is involved in the control of cell growth and differentiation.
Bio References	Aifa, S., et al., Exp. Cell Res. 302(1):108-114 (2005). Adams, T.E., et al., Growth Factors 22(2):89-95 (2004). Ichinose, J., et al., Biochem. Biophys. Res. Commun. 324(3):1143-1149 (2004). Kuribayashi, A., et al., Endocrinology 145(11):4976-4984 (2004). Kapoor, G.S., et al., Mol. Cell. Biol. 24(2):823-836 (2004).
Gene ID	1956
Gene Name	EGFR (HGNC:3236)
Reactivity	H
Predicted	M
Calculated MW	134277
Antigen Source	HUMAN
Target/Specificity	This EGFR Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding Y1016 of human EGFR.
NCBI Accession	NP_005219.2; NP_958439.1; NP_958440.1; NP_958441.1

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