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HSPA5 Antibody (C-term)

HSPA5 Antibody (C-term)

ArtNr	ABC-AP5041b-ev
Hersteller	Abcepta
Menge	80 ul
Kategorie	Oncology Antibodies By Cell Type Hematology Myeloma Flow Cytometry Immunohistochemistry Western Blot Primary Antibodies
Typ	Antibody Polyclonal
Applikationen	WB, FC, IHC-P
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
Citations	Zhao, C., et al. J. Med. Virol. 82(1):14-22(2010) Zhuang, L., et al. Mod. Pathol. 23(1):45-53(2010) Arnaudeau, S., et al. Proteomics 9(23):5316-5327(2009)
NCBI	NP_005338.1
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	78 kDa glucose-regulated protein,GRP-78,Endoplasmic reticulum lumenal Ca(2+)-binding protein grp78,Heat shock 70 kDa protein 5,Immunoglobulin heavy chain-binding protein,BiP,HSPA5,GRP78
Similar products	GRP-78, HSPA5, GRP78, 78 kDa glucose-regulated protein, Endoplasmic reticulum lumenal Ca(2+)-binding protein grp78, Heat shock 70 kDa protein 5, Immunoglobulin heavy chain-binding protein, BiP
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Manufacturer - Category	Primary Antibodies; Apoptosis signaling
Manufacturer - Targets	This HSPA5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 541-568 amino acids from the C-terminal region of human HSPA5.
Bio Background	When Chinese hamster K12 cells are starved of glucose, thesynthesis of several proteins, called glucose-regulated proteins(GRPs), is markedly increased. Hendershot et al. (1994) [PubMed82977] pointed out that one of these, GRP78 (HSPA5), alsoreferred to as 'immunoglobulin heavy chain-binding protein' (BiP), is a member of the heat-shock protein-7 (HSP7) family and isinvolved in the folding and assembly of proteins in the endoplasmicreticulum (ER). Because so many ER proteins interact transientlywith GRP78, it may play a key role in monitoring protein transportthrough the cell.
Clonality	Polyclonal
Polyclonal Antibody Additonal Information	RB20814
Gene Name	HSPA5
Subtitle	Affinity Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	H
Predicted Reactivity	B, Ha, M, Pig, Rat, X
Calculated Molecular Weight	72333
Antigen Source	HUMAN
Antigen Region	541-568
Formulation	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Dilution	WB: 1:1000 IHC-P: 1:50~100 FC: 1:10~50
Antigen Type	Synthetic Peptide

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Menge: 80 ul

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