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HSPA5 Antibody (C-term)

HSPA5 Antibody (C-term)

Item no.	ABC-AP5041b-ev
Manufacturer	Abcepta
Amount	80 ul
Category	Oncology Antibodies By Cell Type Hematology Myeloma Flow Cytometry Immunohistochemistry Western Blot Primary Antibodies
Type	Antibody Polyclonal
Applications	WB, FC, IHC-P
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
Citations	Zhao, C., et al. J. Med. Virol. 82(1):14-22(2010) Zhuang, L., et al. Mod. Pathol. 23(1):45-53(2010) Arnaudeau, S., et al. Proteomics 9(23):5316-5327(2009)
NCBI	NP_005338.1
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	78 kDa glucose-regulated protein,GRP-78,Endoplasmic reticulum lumenal Ca(2+)-binding protein grp78,Heat shock 70 kDa protein 5,Immunoglobulin heavy chain-binding protein,BiP,HSPA5,GRP78
Similar products	GRP-78, HSPA5, GRP78, 78 kDa glucose-regulated protein, Endoplasmic reticulum lumenal Ca(2+)-binding protein grp78, Heat shock 70 kDa protein 5, Immunoglobulin heavy chain-binding protein, BiP
Available
Manufacturer - Category	Primary Antibodies; Apoptosis signaling
Manufacturer - Targets	This HSPA5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 541-568 amino acids from the C-terminal region of human HSPA5.
Bio Background	When Chinese hamster K12 cells are starved of glucose, thesynthesis of several proteins, called glucose-regulated proteins(GRPs), is markedly increased. Hendershot et al. (1994) [PubMed82977] pointed out that one of these, GRP78 (HSPA5), alsoreferred to as 'immunoglobulin heavy chain-binding protein' (BiP), is a member of the heat-shock protein-7 (HSP7) family and isinvolved in the folding and assembly of proteins in the endoplasmicreticulum (ER). Because so many ER proteins interact transientlywith GRP78, it may play a key role in monitoring protein transportthrough the cell.
Clonality	Polyclonal
Polyclonal Antibody Additonal Information	RB20814
Gene Name	HSPA5
Subtitle	Affinity Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	H
Predicted Reactivity	B, Ha, M, Pig, Rat, X
Calculated Molecular Weight	72333
Antigen Source	HUMAN
Antigen Region	541-568
Formulation	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Dilution	WB: 1:1000 IHC-P: 1:50~100 FC: 1:10~50
Antigen Type	Synthetic Peptide

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 80 ul

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Delivery expected until 3/5/2026

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