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KRT10 Antibody (Center)

KRT10 Antibody (Center)

ArtNr	ABC-AP6704c
Hersteller	Abcepta
Menge	400 ul
Kategorie	Antibodies Primary Antibodies
Typ	Antibody Primary
Format	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Applikationen	WB, FC, IHC-P
Specific against	other
Host	Rabbit
Isotype	Ig
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Similar products	Keratin, KRT10, CK-10, K10, KPP, type I cytoskeletal 10, Cytokeratin-10, Keratin-10
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Primary Accession	P13645
Antigen Type	Synthetic Peptide
Application	FC, IHC-P, WB
Bio Background	KRT10 is a member of the type I (acidic) cytokeratin family, which belongs to the superfamily of intermediate filament (IF) proteins. Keratins are heteropolymeric structural proteins which form the intermediate filament. These filaments, along with actin microfilaments and microtubules, compose the cytoskeleton of epithelial cells. Mutations in its gene are associated with epidermolytic hyperkeratosis.
Bio References	Morais, P., Eur J Dermatol 19 (4), 333-336 (2009) Barcelos, A.C., J. Cutan. Pathol. 36 (6), 647-654 (2009)
Clonality	Polyclonal
Clone/Animal Names	RB18413
Gene ID	3858
Gene Name	KRT10
Subtitle	Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	H
Legend image 1	Western blot analysis of KRT10 antibody (Center) (Cat. #AP6704c) in CEM cell line lysates (35ug/lane). KRT10 (arrow) was detected using the purified Pab.
Type image 1	WB
Dilution image 1	1:1000
Legend image 2	Formalin-fixed and paraffin-embedded human skin reacted with KRT10 Antibody (Center), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
Type image 2	IHC-P
Dilution image 2	1:50~100
Legend image 3	KRT10 Antibody (Center) (Cat. #AP6704c) flow cytometric analysis of CEM cells (bottom histogram) compared to a negative control cell (top histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Type image 3	FC
Dilution image 3	1:10~50
Other Accession	Q6IFW6
Predicted	Rat
Isotype	Rabbit Ig
Calculated MW	58827
Antigen Region	318-346
Antigen Source	HUMAN
Target/Specificity	This KRT10 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 318-346 amino acids from the Central region of human KRT10.
NCBI Accession	NP_000412.3

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Menge: 400 ul

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