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SERPINC1 Antibody (C-term)

SERPINC1 Antibody (C-term)

ArtNr	ABC-AP6715b-ev
Hersteller	Abcepta
Menge	80 ul
Kategorie	Antibodies Primary Antibodies
Typ	Antibody Primary
Format	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Applikationen	WB, FC, IF, IHC-P
Specific against	other
Host	Rabbit
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Similar products	SERPINC1, AT3, Antithrombin-III, Serpin C1, ATIII
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Primary Accession	P01008
Antigen Type	Synthetic Peptide
Application	WB, IF, FC, IHC-P
Bio Background	SERPINC1 is a plasma protease inhibitor and a member of the serpin superfamily. This protein inhibits thrombin as well as other activated serine proteases of the coagulation system, and it regulates the blood coagulation cascade. The protein includes two functional domains: the heparin binding-domain at the N-terminus of the mature protein, and the reactive site domain at the C-terminus. The inhibitory activity is enhanced by the presence of heparin.
Bio References	Doi, T., Arch. Biochem. Biophys. 489 (1-2), 62-67 (2009) Sun, X.J., J. Biol. Chem. 264 (19), 11288-11293 (1989)
Clonality	Polyclonal
Clone/Animal Names	RB18489
Gene ID	462
Gene Name	SERPINC1
Subtitle	Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	H, M
Legend image 1	Confocal immunofluorescent analysis of SERPINC1 Antibody (C-term)(Cat. #AP6715b) with 293 cell followed by Alexa Fluor® 488-conjugated goat anti-rabbit lgG (green). DAPI was used to stain the cell nuclear (blue).
Type image 1	IF
Dilution image 1	1:10~50
Legend image 2	Western blot analysis of SERPINC1 Antibody (C-term) (Cat. #AP6715b) in mouse liver tissue lysates (35ug/lane). SERPINC1 (arrow) was detected using the purified Pab.
Type image 2	WB
Dilution image 2	1:1000
Legend image 3	Western blot analysis of lysate from human blood plasma tissue lysate, using SERPINC1 Antibody (C-term)(Cat. #AP6715b). AP6715b was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:5000 dilution was used as the secondary antibody. Lysate at 35ug per lane.
Type image 3	WB
Dilution image 3	1:1000
Legend image 4	Formalin-fixed and paraffin-embedded human hepatocarcinoma reacted with SERPINC1 Antibody (C-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
Type image 4	IHC-P
Dilution image 4	1:50~100
Legend image 5	SERPINC1 Antibody (C-term) (Cat. #AP6715b) flow cytometric analysis of HepG2 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Type image 5	FC
Dilution image 5	1:10~50
Isotype	Rabbit Ig
Calculated MW	52602
Antigen Region	364-393
Antigen Source	HUMAN
Target/Specificity	This SERPINC1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 364-393 amino acids from the C-terminal region of human SERPINC1.
NCBI Accession	NP_000479.1

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Menge: 80 ul

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