Vergleich

MYT1 (PKMYT1) Antibody (C-term)

ArtNr ABC-AP7196b
Hersteller Abcepta
Menge 400 ul
Kategorie
Typ Antibody Primary
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Applikationen WB
Specific against other
Host Rabbit
Isotype Ig
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Similar products PKMYT1, MYT1, Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase, Myt1 kinase
Lieferbar
Primary Accession
Q99640
Antigen Type
Synthetic Peptide
Application
WB
Bio Background
The protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase preferentially phosphorylates and inactivates cell division cycle 2 protein (CDC2), and thus negatively regulates cell cycle G2/M transition. This kinase is associated with the membrane throughout the cell cycle. Its activity is highly regulated during the cell cycle. Protein kinases AKT1/PKB and PLK (Polo-like kinase) have been shown to phosphorylate and regulate the activity of this kinase. Alternatively spliced transcript variants encoding distinct isoforms have been reported. Transcript Variant: This variant (1) encodes the longer isoform (1).
Bio References
Dai, X., et al., J. Invest. Dermatol. 122(6):1356-1364 (2004).
Nakajima, H., et al., J. Biol. Chem. 278(28):25277-25280 (2003).
Passer, B.J., et al., Proc. Natl. Acad. Sci. U.S.A. 100(5):2284-2289 (2003).
Okumura, E., et al., Nat. Cell Biol. 4(2):111-116 (2002).
Booher, R.N., et al., J. Biol. Chem. 272(35):22300-22306 (1997).
Clonality
Polyclonal
Clone/Animal Names
RB09867
Gene ID
9088
Gene Name
PKMYT1
Subtitle
Purified Rabbit Polyclonal Antibody (Pab)
Reactivity
H
Legend image 1
Western blot analysis of anti-PKMYT1 Pabin A375(left) and Y79 (right)cell line lysate. PKMYT1(arrow) was detected using the purified Pab.
Type image 1
WB
Dilution image 1
1:1000
Legend image 2
Western blot analysis of PKMYT1 (arrow) using rabbit polyclonal PKMYT1 C-term (Cat. #AP7196b). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the PKMYT1 gene.
Type image 2
WB
Dilution image 2
1:1000
Isotype
Rabbit Ig
Calculated MW
54521
Antigen Region
452-482
Antigen Source
HUMAN
Target/Specificity
This MYT1 (PKMYT1) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 452-482 amino acids from the C-terminal region of human MYT1 (PKMYT1).
NCBI Accession
NP_001245379.1; NP_001245380.1; NP_004194.3; NP_872629.1

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 400 ul
Lieferbar: In stock
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