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Neprilysin Antibody (C-term)

Neprilysin Antibody (C-term)

ArtNr	ABC-AP7329B
Hersteller	Abcepta
Menge	400 ul
Kategorie	Antibodies Primary Antibodies
Typ	Antibody Primary
Format	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Applikationen	WB, FC, IHC-P
Specific against	other
Host	Rabbit
Isotype	Ig
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Similar products	CD10, MME, EPN, Neprilysin, Atriopeptidase, Common acute lymphocytic leukemia antigen, Enkephalinase, Skin fibroblast elastase, NEP, CALLA, SFE, Neutral endopeptidase, Neutral endopeptidase 2411
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Primary Accession	P08473
Antigen Type	Synthetic Peptide
Application	FC, IHC-P, WB
Bio Background	MME is a common acute lymphocytic leukemia antigen that is an important cell surface marker in the diagnosis of human acute lymphocytic leukemia (ALL). This protein is present on leukemic cells of pre-B phenotype, which represent 85% of cases of ALL. This protein is not restricted to leukemic cells, however, and is found on a variety of normal tissues. It is a oprotein that is particularly abundant in kidney, where it is present on the brush border of proximal tubules and on glomerular epithelium. The protein is a neutral endopeptidase that cleaves peptides at the amino side of hydrophobic residues and inactivates several peptide hormones including glucagon, enkephalins, substance P, neurotensin, oxytocin, and bradykinin.
Bio References	Dakka, N., Bellaoui, H. Pediatr Hematol Oncol 26 (4), 216-231 (2009) Wang, R., Wang, S. J. Neurochem. 108 (4), 1072-1082 (2009) Shipp, M.A. Proc. Natl. Acad. Sci. U.S.A. 88 (23), 10662-10666 (1991) Shipp, M.A. Proc. Natl. Acad. Sci. U.S.A. 86 (1), 297-301 (1989)
Clonality	Polyclonal
Clone/Animal Names	RB18821
Gene ID	4311
Gene Name	MME
Subtitle	Affinity Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	H
Legend image 1	Western blot analysis of Neprilysin Antibody (C-term) (Cat. #AP7329b) in A2058, A375, Ramos cell line lysates (35ug/lane). EPN (arrow) was detected using the purified Pab.
Type image 1	WB
Dilution image 1	1:1000
Legend image 2	Formalin-fixed and paraffin-embedded human kidney carcinoma with Neprilysin Antibody (C-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
Type image 2	IHC-P
Dilution image 2	1:50~100
Legend image 3	Neprilysin Antibody (C-term) (Cat. #AP7329b) flow cytometry analysis of Ramos cells (bottom histogram) compared to a negative control cell (top histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Type image 3	FC
Dilution image 3	1:10~50
Other Accession	P07861; P08049; Q61391
Predicted	M, Rb, Rat
Isotype	Rabbit Ig
Calculated MW	85514
Antigen Region	506-534
Antigen Source	HUMAN
Target/Specificity	This Neprilysin antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 506-534 amino acids from the C-terminal region of human Neprilysin.
NCBI Accession	NP_000893.2; NP_009218.2; NP_009219.2; NP_009220.2

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ABC-AP7329B-datasheet.pdf

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Menge: 400 ul

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Lieferung vsl. bis 02.10.2025

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