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PDGFRA Antibody (Y762)

PDGFRA Antibody (Y762)

Hersteller	Abcepta
Kategorie	Antibodies Primary Antibodies
Typ	Antibody Primary
Specific against	other
Isotype	Ig
Format	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Applikationen	WB, IHC-P
Menge	400 ul
Host	Rabbit
ArtNr	ABC-AP7666F
eClass 6.1	32160702
eClass 9.0	32160702
Lieferbar
Primary Accession	P16234
Antigen Type	Synthetic Peptide
Application	IHC-P, WB
Bio Background	PDGFRA is a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. Studies in knockout mice, where homozygosity is lethal, indicate that the alpha form of the platelet-derived growth factor receptor is particularly important for kidney development since mice heterozygous for the receptor exhibit defective kidney phenotypes.
Bio References	Wilczynski, S.P., et al., Hum. Pathol. 36(3):242-249 (2005). Hiwatari, M., et al., Leukemia 19(3):476-477 (2005). Debiec-Rychter, M., et al., Gastroenterology 128(2):270-279 (2005). Sakurai, S., et al., Hum. Pathol. 35(10):1223-1230 (2004). Subramanian, S., et al., Oncogene 23(47):7780-7790 (2004).
Clonality	Polyclonal
Clone/Animal Names	RB11109
Gene ID	5156
Gene Name	PDGFRA
Subtitle	Affinity Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	H
Legend image 1	Western blot analysis of PDGFRA (arrow) using rabbit polyclonal PDGFRA Antibody (Y762) (RB11109). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the PDGFRA gene (Lane 2) (Origene Technologies).
Type image 1	WB
Dilution image 1	1:1000
Legend image 2	Formalin-fixed and paraffin-embedded human prostata carcinoma tissue reacted with PDGFRA Antibody (Y762) (Cat.#AP7666f), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
Type image 2	IHC-P
Dilution image 2	1:10~50
Other Accession	P26619; P20786; P26618; NP_006197
Predicted	M, Rat, X
Isotype	Rabbit Ig
Calculated MW	122670
Antigen Region	740-769
Antigen Source	HUMAN
Target/Specificity	This PDGFRA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 740-769 amino acids from human PDGFRA.
NCBI Accession	NP_006197.1

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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ABC-AP7666F-datasheet.pdf

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Menge: 400 ul

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Lieferung vsl. bis 04.07.2024

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