TrkA Antibody

ArtNr	ABC-AP7686F-ev-80ul
Hersteller	Abcepta
Menge	80 ul
Kategorie	Oncology Neuroscience Neural Lineage Markers Metabolism Diabetes Molecular Targets for Neuroscience Targets for Rodent Neurosciences Neural Signaling Antibodies Blastoma Carcinoma Hematology Leukemia Lymphoma Myeloma Melanoma Sarcoma Cell Biology Cell Status Necrosis Cytoskeleton Flow Cytometry Western Blot Immunofluorescence Motor proteins Primary Antibodies Microfilaments Colorectal Cancer Thyroid Cancer
Typ	Antibody Polyclonal
Applikationen	Immunofluorescence, Western Blot, Flow cytometry
Specific against	other
Host	Rabbit
Isotype	Ig
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	High affinity nerve growth factor receptor, Neurotrophic tyrosine kinase receptor type 1, TRK1-transforming tyrosine kinase protein, Tropomyosin-related kinase A, Tyrosine kinase receptor, Tyrosine kinase receptor A, Trk-A, gp140trk, p140-TrkA, NTRK1, MTC
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Primary Accession	P04629
Antigen Type	Recombinant Protein
Bio Background	TRKA (also known as NTRK1)is a member of the neurotrophic tyrosine kinase receptor (NTKR) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. The presence of this kinase leads to cell differentiation and may play a role in specifying sensory neuron subtypes. Mutations in the TRKA gene have been associated with congenital insensitivity to pain, anhidrosis, self-mutilating behavior, mental retardation and cancer.
Bio References	Tokusashi, Y., et al., Int. J. Cancer 114(1):39-45 (2005). Schulte, J.H., et al., Oncogene 24(1):165-177 (2005). Frattini, M., et al., Oncogene 23(44):7436-7440 (2004). Tacconelli, A., et al., Cancer Cell 6(4):347-360 (2004). Florenes, V.A., et al., Am. J. Clin. Pathol. 122(3):412-420 (2004).
Gene ID	4914
Gene Name	NTRK1
Reactivity	H, M
Calculated MW	87497
Antigen Region	his fusion protein
Antigen Source	HUMAN
Target/Specificity	This TrkA antibody is generated from rabbits immunized with TrkA his fusion protein
NCBI Accession	NP_001007793.1; NP_001012331.1; NP_002520.2

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Menge: 80 ul

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