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MEK4 (MAP2K4) Antibody (S257)

MEK4 (MAP2K4) Antibody (S257)

ArtNr	ABC-AP7916D-ev-80ul
Hersteller	Abcepta
Menge	80 ul
Kategorie	Oncology Neuroscience Molecular Targets for Neuroscience Neural Signaling Antibodies Blastoma Carcinoma Glioma Hematology Lymphoma Myeloma Melanoma Sarcoma Cell Biology Cell Status Immunohistochemistry Western Blot Senescence Primary Antibodies Bladder Cancer
Typ	Antibody Polyclonal
Applikationen	Western Blot, Immunohistochemistry
Specific against	other
Host	Rabbit
Isotype	Ig
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Dual specificity mitogen-activated protein kinase kinase 4, MAP kinase kinase 4, MAPKK 4, JNK-activating kinase 1, MAPK/ERK kinase 4, MEK 4, SAPK/ERK kinase 1, SEK1, Stress-activated protein kinase kinase 1, SAPK kinase 1, SAPKK-1, SAPKK1, c-Jun N-termina
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Primary Accession	P45985
Other Accession	P47809; Q07192; Q9DGR7
Antigen Type	Synthetic Peptide
Bio Background	MAP2K4 is a dual specificity protein kinase that belongs to the Ser/Thr protein kinase family. This kinase is a direct activator of MAP kinases in response to various environmental stresses or mitogenic stimuli. It has been shown to activate MAPK8/JNK1, MAPK9/JNK2, and MAPK14/p38, but not MAPK1/ERK2 or MAPK3/ERK3. MAP2K4 is phosphorylated, and thus activated by MAP3K1/MEKK. The knockout studies in mice suggested the roles of this kinase in mediating survival signal in T cell development, as well as in the organogenesis of liver.
Bio References	Robinson, V.L., Mol. Cancer Res. 6 (3), 501-508 (2008) Zhang, H., J. Biol. Chem. 282 (20), 14788-14796 (2007) Salmeron, A., EMBO J. 15 (4), 817-826 (1996)
Gene ID	6416
Gene Name	MAP2K4
Reactivity	H
Predicted	Zf, X, M
Calculated MW	44288
Antigen Region	235-264
Antigen Source	HUMAN
Target/Specificity	This MEK4(MAP2K4) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 235-264 amino acids from human MEK4(MAP2K4).
NCBI Accession	NP_001268364.1; NP_003001.1

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Menge: 80 ul

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