CCR3 Antibody (Center)

Synthetic Peptide

CCR3 is a receptor for C-C type chemokines. It belongs to family 1 of the G protein-coupled receptors. This receptor binds and responds to a variety of chemokines, including eotaxin (CCL11), eotaxin-3 (CCL26), MCP-3 (CCL7), MCP-4 (CCL13), and RANTES (CCL5). It is highly expressed in eosinophils and basophils, and is also detected in TH1 and TH2 cells, as well as in airway epithelial cells. This receptor may contribute to the accumulation and activation of eosinophils and other inflammatory cells in the allergic airway. It is also known to be an entry co-receptor for HIV-1.

Polyclonal

1232

Affinity Purified Rabbit Polyclonal Antibody (Pab)

Western blot analysis of CCR3 Antibody (Center) (Cat. #AP8806c) in Jurkat cell line lysates (35ug/lane). CCR3 (arrow) was detected using the purified Pab.

1:1000

FC

Q9BDS8

Rabbit Ig

291-318

This CCR3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 291-318 amino acids from the Central region of human CCR3.