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CCR3 Antibody (Center)

CCR3 Antibody (Center)

Item no.	ABC-AP8806c
Manufacturer	Abcepta
Amount	400 ul
Category	Antibodies Primary Antibodies
Type	Antibody Primary
Format	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Applications	WB, FC
Specific against	other
Host	Rabbit
Isotype	Ig
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Similar products	CCR-3, CCR3, CC-CKR-3, CD193, CKR3, CMKBR3, C-C chemokine receptor type 3, C-C CKR-3, Eosinophil eotaxin receptor
Available
Primary Accession	P51677
Antigen Type	Synthetic Peptide
Application	FC, WB
Bio Background	CCR3 is a receptor for C-C type chemokines. It belongs to family 1 of the G protein-coupled receptors. This receptor binds and responds to a variety of chemokines, including eotaxin (CCL11), eotaxin-3 (CCL26), MCP-3 (CCL7), MCP-4 (CCL13), and RANTES (CCL5). It is highly expressed in eosinophils and basophils, and is also detected in TH1 and TH2 cells, as well as in airway epithelial cells. This receptor may contribute to the accumulation and activation of eosinophils and other inflammatory cells in the allergic airway. It is also known to be an entry co-receptor for HIV-1.
Bio References	Ponath, P.D., et.al., J. Clin. Invest. 97 (3), 604-612 (1996)
Clonality	Polyclonal
Clone/Animal Names	RB22038
Gene ID	1232
Gene Name	CCR3
Subtitle	Affinity Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	H
Legend image 1	Western blot analysis of CCR3 Antibody (Center) (Cat. #AP8806c) in Jurkat cell line lysates (35ug/lane). CCR3 (arrow) was detected using the purified Pab.
Type image 1	WB
Dilution image 1	1:1000
Legend image 2	CCR3 Antibody (Center) (Cat. #AP8806c) flow cytometry analysis of Jurkat cells (bottom histogram) compared to a negative control cell (top histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Type image 2	FC
Dilution image 2	1:10~50
Other Accession	Q9BDS8
Predicted	Pr
Isotype	Rabbit Ig
Calculated MW	41044
Antigen Region	291-318
Antigen Source	HUMAN
Target/Specificity	This CCR3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 291-318 amino acids from the Central region of human CCR3.
NCBI Accession	NP_001828.1; NP_847898.1; NP_847899.1

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 400 ul

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Delivery expected until 9/4/2025

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