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ARG1 Antibody (C-term)

ARG1 Antibody (C-term)

ArtNr	ABC-AP8976b-ev
Hersteller	Abcepta
Menge	80 ul
Kategorie	Antibodies Primary Antibodies
Typ	Antibody Primary
Format	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Applikationen	WB, FC, IHC-P
Specific against	other
Host	Rabbit
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Similar products	ARG1, Arginase-1, Liver-type arginase, Type I arginase
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Primary Accession	P05089
Antigen Type	Synthetic Peptide
Application	FC, IHC-P, WB
Bio Background	Arginase catalyzes the hydrolysis of arginine to ornithine and urea. At least two isoforms of mammalian arginase exist (types I and II) which differ in their tissue distribution, subcellular localization, immunologic crossreactivity and physiologic function. The type I isoform encoded by this gene, is a cytosolic enzyme and expressed predominantly in the liver as a component of the urea cycle. Inherited deficiency of this enzyme results in argininemia, an autosomal recessive disorder characterized by hyperammonemia.
Bio References	Haraguchi, Y., et.al., J. Clin. Invest. 86 (1), 347-350 (1990)
Clonality	Polyclonal
Clone/Animal Names	RB23044
Gene ID	383
Gene Name	ARG1
Subtitle	Affinity Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	H
Legend image 1	Western blot analysis of ARG1 Antibody (C-term) (Cat. #AP8976b) in MDA-MB231 cell line lysates (35ug/lane). ARG1 (arrow) was detected using the purified Pab.
Type image 1	WB
Dilution image 1	1:1000
Legend image 2	Formalin-fixed and paraffin-embedded human hepatocarcinoma reacted with ARG1 Antibody (C-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
Type image 2	IHC-P
Dilution image 2	1:50~100
Legend image 3	ARG1 Antibody (C-term) (Cat. #AP8976b) flow cytometric analysis of MDA-MB231 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Type image 3	FC
Dilution image 3	1:10~50
Isotype	Rabbit Ig
Calculated MW	34735
Antigen Region	293-322
Antigen Source	HUMAN
Target/Specificity	This ARG1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 293-322 amino acids from the C-terminal region of human ARG1.
NCBI Accession	NP_000036.2; NP_001231367.1

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