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CIRBP Antibody (C-term)

ArtNr ABC-AP9139b
Hersteller Abcepta
Menge 400 ul
Kategorie
Typ Antibody Polyclonal
Applikationen WB, IHC-P
Specific against Human (Homo sapiens)
Host Rabbit
Isotype IgG
Citations Colinge J., et.al., Submitted (OCT-2008) to UniProtKB.
Yang R.,et.al., Nucleic Acids Res. 34:1224-1236(2006).
NCBI NP_001271.1
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias Cold-inducible RNA-binding protein,A18 hnRNP,Glycine-rich RNA-binding protein CIRP,CIRBP,A18HNRNP,CIRP
Similar products CIRBP, CIRP, Cold-inducible RNA-binding protein, A18HNRNP, A18 hnRNP, Glycine-rich RNA-binding protein CIRP
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Manufacturer - Category
Primary Antibodies; Cell Biology; Stress response
Manufacturer - Targets
This CIRBP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 145-172 amino acids from the C-terminal region of human CIRBP.
Bio Background
CIRBP is cold-inducible mRNA binding protein that plays a protective role in the genotoxic stress response by stabilizing transcripts of genes involved in cell survival. It acts as a translational activator and seems to play an essential role in cold-induced suppression of cell proliferation. It binds specifically to the 3'-untranslated regions (3'-UTRs) of stress-responsive transcripts RPA2 and TXN. This protein acts as a translational repressor (By similarity) and promotes assembly of stress granules (SGs), when overexpressed.
Clonality
Polyclonal
Polyclonal Antibody Additonal Information
RB23135
Gene Name
CIRBP
Subtitle
Affinity Purified Rabbit Polyclonal Antibody (Pab)
Reactivity
H
Predicted Reactivity
Ha, M, Rat
Calculated Molecular Weight
18648
Antigen Source
HUMAN
Antigen Region
145-172
Formulation
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Dilution
WB: 1:1000
WB: 1:1000
IHC-P: 1:50~100
Antigen Type
Synthetic Peptide

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 400 ul
Lieferbar: In stock
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