Comparison

CIRBP Antibody (C-term)

Item no. ABC-AP9139b
Manufacturer Abcepta
Amount 400 ul
Category
Type Antibody Primary
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Applications WB, IHC-P
Specific against other
Host Rabbit
Isotype Ig
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Similar products CIRBP, CIRP, Cold-inducible RNA-binding protein, A18HNRNP, A18 hnRNP, Glycine-rich RNA-binding protein CIRP
Available
Primary Accession
Q14011
Antigen Type
Synthetic Peptide
Application
WB, IHC-P
Bio Background
CIRBP is cold-inducible mRNA binding protein that plays a protective role in the genotoxic stress response by stabilizing transcripts of genes involved in cell survival. It acts as a translational activator and seems to play an essential role in cold-induced suppression of cell proliferation. It binds specifically to the 3'-untranslated regions (3'-UTRs) of stress-responsive transcripts RPA2 and TXN. This protein acts as a translational repressor (By similarity) and promotes assembly of stress granules (SGs), when overexpressed.
Bio References
Colinge J., et.al., Submitted (OCT-2008) to UniProtKB.
Yang R., et.al., Nucleic Acids Res. 34:1224-1236(2006).
Clonality
Polyclonal
Clone/Animal Names
RB23135
Gene ID
1153
Gene Name
CIRBP
Subtitle
Affinity Purified Rabbit Polyclonal Antibody (Pab)
Reactivity
H
Legend image 1
Western blot analysis of CIRBP Antibody (C-term) (Cat. #AP9139b) in Y79 cell line lysates (35ug/lane). CIRBP (arrow) was detected using the purified Pab.
Type image 1
WB
Dilution image 1
1:1000
Legend image 2
Western blot analysis of CIRBP (arrow) using rabbit polyclonal CIRBP Antibody (C-term) (Cat. #AP9139b). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the CIRBP gene.
Type image 2
WB
Dilution image 2
1:1000
Legend image 3
CIRBP Antibody (C-term) (Cat. #AP9139b) IHC analysis in formalin fixed and paraffin embedded human lung carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the CIRBP Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.
Type image 3
IHC-P
Dilution image 3
1:50~100
Other Accession
P60825; P60824; P60826
Predicted
Ha, M, Rat
Isotype
Rabbit Ig
Calculated MW
18648
Antigen Region
145-172
Antigen Source
HUMAN
Target/Specificity
This CIRBP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 145-172 amino acids from the C-terminal region of human CIRBP.
NCBI Accession
NP_001271.1

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 400 ul
Available: In stock
available

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