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C10orf4 Antibody (monoclonal) (M02)

C10orf4 Antibody (monoclonal) (M02)

ArtNr	ABC-AT1325a
Hersteller	Abcepta
Menge	100 ug
Kategorie	Antibodies Primary Antibodies
Typ	Antibody Primary
Format	Clear, colorless solution in phosphate buffered saline, pH 7.2 .
Applikationen	WB
Clon	2C4
Specific against	other
Host	Mouse
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Similar products	C10orf4, FRA10AC1, Protein FRA10AC1
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Primary Accession	Q70Z53
Antigen Type	Recombinant Protein
Application	WB
Bio Background	The protein encoded by this gene is a nuclear phosphoprotein of unknown function. The 5' UTR of this gene is part of a CpG island and contains a tandem CGG repeat region that normally consists of 8-14 repeats but can expand to over 200 repeats. The expanded allele becomes hypermethylated and is not transcribed; however, an expanded repeat region has not been associated with any disease phenotype. This gene is found within the rare FRA10A folate-sensitive fragile site.
Bio References	A scan of chromosome 10 identifies a novel locus showing strong association with late-onset Alzheimer disease. Grupe A, et al. Am J Hum Genet, 2006 Jan. PMID 16385451.A human protein-protein interaction network: a resource for annotating the proteome. Stelzl U, et al. Cell, 2005 Sep 23. PMID 16169070.The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Gerhard DS, et al. Genome Res, 2004 Oct. PMID 15489334.Folate-sensitive fragile site FRA10A is due to an expansion of a CGG repeat in a novel gene, FRA10AC1, encoding a nuclear protein. Sarafidou T, et al. Genomics, 2004 Jul. PMID 15203205.The DNA sequence and comparative analysis of human chromosome 10. Deloukas P, et al. Nature, 2004 May 27. PMID 15164054.
Clonality	Monoclonal
Gene ID	118924
Gene Name	FRA10AC1
Subtitle	Mouse monoclonal antibody raised against a partial recombinant C10orf4.
Reactivity	H, Rat
Legend image 1	Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (36.74 KDa) .
Type image 1	WB
Dilution image 1	1:500~1000
Legend image 2	C10orf4 monoclonal antibody (M02), clone 2C4 Western Blot analysis of C10orf4 expression in PC-12 ( (Cat # AT1325a )
Type image 2	WB
Dilution image 2	1:500~1000
Legend image 3	Western Blot analysis of C10orf4 expression in transfected 293T cell line by C10orf4 monoclonal antibody (M02), clone 2C4. Lane 1: C10orf4 transfected lysate(37.6 KDa). Lane 2: Non-transfected lysate.
Type image 3	WB
Dilution image 3	1:500~1000
Other Accession	NM_145246
Isotype	IgG1 Kappa
Antigen Source	Human: ~~ Positive
Target/Specificity	C10orf4 (NP_660289, 1 a.a. ~ 100 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
NCBI Accession	NP_660289.2
	Clone: 2C4
Org Accession	NP_660289
Gene Description	chromosome 10 open reading frame 4

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Menge: 100 ug

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