NR1H4 Antibody (monoclonal) (M01)

Recombinant Protein

The nuclear receptor FXR is expressed in pancreatic beta-cells and protects human islets from lipotoxicity. Popescu IR, et al. FEBS Lett, 2010 Jul 2. PMID 20447400.Bile acids and their nuclear receptor FXR: Relevance for hepatobiliary and gastrointestinal disease. Gadaleta RM, et al. Biochim Biophys Acta, 2010 Jul. PMID 20399894.Genetic risk factors for hepatopulmonary syndrome in patients with advanced liver disease. Roberts KE, et al. Gastroenterology, 2010 Jul. PMID 20346360.Regulation of the human bile acid UDP-glucuronosyltransferase 1A3 by the farnesoid X receptor and bile acids. Erichsen TJ, et al. J Hepatol, 2010 Apr. PMID 20189675.Farnesoid X receptor, through the binding with steroidogenic factor 1-responsive element, inhibits aromatase expression in tumor Leydig cells. Catalano S, et al. J Biol Chem, 2010 Feb 19. PMID 20026603.

9971

Mouse monoclonal antibody raised against a partial recombinant NR1H4.

Immunofluorescence of monoclonal antibody to NR1H4 on HepG2 cell. [antibody concentration 10 ug/ml]

Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (37.84 KDa) .

1:500~1000

WB

NR1H4 monoclonal antibody (M01), clone 1G11. Western Blot analysis of NR1H4 expression in A-431 ( (Cat # AT3098a )

1:500~1000

E

IgG1 Kappa

NR1H4 (NP_005114, 363 a.a. ~ 472 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Clone: 1G11

nuclear receptor subfamily 1, group H, member 4