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PCNA Antibody (monoclonal) (M02)

PCNA Antibody (monoclonal) (M02)

ArtNr	ABC-AT3236a
Hersteller	Abcepta
Menge	100 ug
Kategorie	Oncology Neuroscience Neural Lineage Markers Antibodies By Cell Type Blastoma Carcinoma Cell Biology Cell Status Immunoprecipitation Western Blot ELISA Immunofluorescence Proliferation Primary Antibodies By Organ Bladder Cancer Immunostaining
Typ	Antibody Monoclonal
Format	Liquid
Applikationen	WB, IF, IP, ELISA
Clon	1G7
Specific against	Human (Homo sapiens)
Host	Mouse
Isotype	IgG2a Kappa
Citations	1.The RAD51-stimulatory compound RS-1 can exploit the RAD51 overexpression that exists in cancer cells and tumors.Mason JM, Logan HL, Budke B, Wu M, Pawlowski M, Weichselbaum RR, Kozikowski AP, Bishop DK, Connell PPCancer Res. 2014 Apr 21.
NCBI	NP_002583.1,NP_872590.1
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	Proliferating cell nuclear antigen,PCNA,Cyclin,PCNA
Similar products	PCNA, Cyclin, Proliferating cell nuclear antigen
Lieferbar
Manufacturer - Targets	PCNA (AAH00491, 1 a.a. ~ 261 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Bio Background	The protein encoded by this gene is found in the nucleus and is a cofactor of DNA polymerase delta. The encoded protein acts as a homotrimer and helps increase the processivity of leading strand synthesis during DNA replication. In response to DNA damage, this protein is ubiquitinated and is involved in the RAD6-dependent DNA repair pathway. Two transcript variants encoding the same protein have been found for this gene. Pseudogenes of this gene have been described on chromosome 4 and on the X chromosome.
Clonality	Monoclonal
Gene Name	PCNA
Subtitle	Mouse monoclonal antibody raised against a full length recombinant PCNA.
Reactivity	H
Antigen Source	Human: ~~ Positive
Formulation	Clear, colorless solution in phosphate buffered saline, pH 7.2 .
Dilution	IF IP WB: 1:500~1000 WB: 1:500~1000 WB: 1:500~1000
Org Accession	AAH00491
Gene Description	proliferating cell nuclear antigen
Gene Summary	The protein encoded by this gene is found in the nucleus and is a cofactor of DNA polymerase delta. The encoded protein acts as a homotrimer and helps increase the processivity of leading strand synthesis during DNA replication. In response to DNA damage, this protein is ubiquitinated and is involved in the RAD6-dependent DNA repair pathway. Two transcript variants encoding the same protein have been found for this gene. Pseudogenes of this gene have been described on chromosome 4 and on the X chromosome. [provided by RefSeq
Antigen Type	Recombinant Protein

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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ABC-AT3236a-datasheet.pdf

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Menge: 100 ug

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Lieferung vsl. bis 01.01.2026

Express-Lieferung: 23 Tage sparen

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