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SOX4 Antibody (monoclonal) (M01)

SOX4 Antibody (monoclonal) (M01)

ArtNr	ABC-AT3999a
Hersteller	Abcepta
Menge	50 ug
Kategorie	Oncology Neuroscience Molecular Targets for Neuroscience Neural Development Antibodies By Cell Type Carcinoma ELISA Primary Antibodies Immunostaining
Typ	Antibody Monoclonal
Format	Liquid
Applikationen	ELISA
Clon	2C5
Specific against	Human (Homo sapiens)
Host	Mouse
Isotype	IgG1 Kappa
Citations	SOX4 overexpression regulates the p53-mediated apoptosis in hepatocellular carcinoma: clinical implication and functional analysis in vitro. Hur W, et al. Carcinogenesis, 2010 Jul. PMID 20400479.Epigenetic repression of microRNA-129-2 leads to overexpression of SOX4 in gastric cancer. Shen R, et al. Biochem Biophys Res Commun, 2010 Apr 16. PMID 20331975.New genetic associations detected in a host response study to hepatitis B vaccine. Davila S, et al. Genes Immun, 2010 Apr. PMID 20237496.Long-range gene regulation links genomic type 2 diabetes and obesity risk regions to HHEX, SOX4, and IRX3. Ragvin A, et al. Proc Natl Acad Sci U S A, 2010 Jan 12. PMID 20080751.CD56 expression in human myeloma cells derived from the neurogenic gene expression: possible role of the SRY-HMG box gene, SOX4. Iqbal MS, et al. Int J Hematol, 2010 Mar. PMID 20049565.
NCBI	NP_003098.1
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	Transcription factor SOX-4,SOX4
Similar products	SOX4, Transcription factor SOX-4
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Manufacturer - Targets	SOX4 (NP_003098, 45 a.a. ~ 136 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Bio Background	This intronless gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins, such as syndecan binding protein (syntenin). The protein may function in the apoptosis pathway leading to cell death as well as to tumorigenesis and may mediate downstream effects of parathyroid hormone (PTH) and PTH-related protein (PTHrP) in bone development. The solution structure has been resolved for the HMG-box of a similar mouse protein.
Clonality	Monoclonal
Gene Name	SOX4 {ECO:0000303\|PubMed:8268656, ECO:0000312\|HGNC:HGNC:11200}
Subtitle	Mouse monoclonal antibody raised against a partial recombinant SOX4.
Reactivity	H
Antigen Source	Human: ~~ Positive
Formulation	Clear, colorless solution in phosphate buffered saline, pH 7.2 .
Org Accession	NP_003098
Gene Description	SRY (sex determining region Y)-box 4
Gene Summary	This intronless gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins, such as syndecan binding protein (syntenin). The protein may function in the apoptosis pathway leading to cell death as well as to tumorigenesis and may mediate downstream effects of parathyroid hormone (PTH) and PTH-related protein (PTHrP) in bone development. The solution structure has been resolved for the HMG-box of a similar mouse protein. [provided by RefSeq
Antigen Type	Recombinant Protein

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Menge: 50 ug

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