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RNPC2 Antibody (monoclonal) (M01)

RNPC2 Antibody (monoclonal) (M01)

ArtNr	ABC-AT3680a
Hersteller	Abcepta
Menge	100 ug
Kategorie	Antibodies Primary Antibodies
Typ	Antibody Primary
Format	Clear, colorless solution in phosphate buffered saline, pH 7.2 .
Applikationen	WB, IF, IHC
Clon	4G8
Specific against	other
Host	Mouse
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Similar products	HCC1, RBM39, RNPC2, RNA-binding protein 39, Hepatocellular carcinoma protein 1, RNA-binding motif protein 39, RNA-binding region-containing protein 2, Splicing factor HCC1, CAPER alpha
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Primary Accession	Q14498
Antigen Type	Recombinant Protein
Application	WB, IHC, IF
Bio Background	The protein encoded by this gene is an RNA binding protein and possible splicing factor. The encoded protein is found in the nucleus, where it colocalizes with core spliceosomal proteins. Studies of a mouse protein with high sequence similarity to this protein suggest that this protein may act as a transcriptional coactivator for JUN/AP-1 and estrogen receptors. Multiple transcript variants encoding different isoforms have been observed for this gene.
Bio References	Genetic ablation of caveolin-1 drives estrogen-hypersensitivity and the development of DCIS-like mammary lesions. Mercier I, et al. Am J Pathol, 2009 Apr. PMID 19342371.CAPERalpha is a novel Rel-TAD-interacting factor that inhibits lymphocyte transformation by the potent Rel/NF-kappaB oncoprotein v-Rel. Dutta J, et al. J Virol, 2008 Nov. PMID 18753212.Toward a confocal subcellular atlas of the human proteome. Barbe L, et al. Mol Cell Proteomics, 2008 Mar. PMID 18029348.Systematic analysis of the protein interaction network for the human transcription machinery reveals the identity of the 7SK capping enzyme. Jeronimo C, et al. Mol Cell, 2007 Jul 20. PMID 17643375.Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. Olsen JV, et al. Cell, 2006 Nov 3. PMID 17081983.
Clonality	Monoclonal
Gene ID	9584
Gene Name	RBM39 {ECO:0000303\|PubMed:28302793, ECO:0000312\|HGNC:HGNC:15923}
Subtitle	Mouse monoclonal antibody raised against a partial recombinant RNPC2.
Reactivity	H, M
Legend image 1	Immunofluorescence of monoclonal antibody to RNPC2 on HeLa cell. [antibody concentration 40 ug/ml]
Type image 1	IF
Legend image 2	Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (31.24 KDa) .
Type image 2	WB
Dilution image 2	1:500~1000
Legend image 3	RNPC2 monoclonal antibody (M01), clone 4G8 Western Blot analysis of RNPC2 expression in Hela S3 NE ( (Cat # AT3680a )
Type image 3	WB
Dilution image 3	1:500~1000
Legend image 4	RNPC2 monoclonal antibody (M01), clone 4G8. Western Blot analysis of RNPC2 expression in NIH/3T3 ( (Cat # AT3680a )
Type image 4	WB
Dilution image 4	1:500~1000
Legend image 5	Western Blot analysis of RBM39 expression in transfected 293T cell line by RNPC2 monoclonal antibody (M01), clone 4G8. Lane 1: RBM39 transfected lysate(58.7 KDa). Lane 2: Non-transfected lysate.
Type image 5	WB
Dilution image 5	1:500~1000
Legend image 6	Immunoperoxidase of monoclonal antibody to RNPC2 on formalin-fixed paraffin-embedded human endometrium. [antibody concentration 1 ug/ml]
Type image 6	IHC
Legend image 7	Detection limit for recombinant GST tagged RNPC2 is approximately 0.03ng/ml as a capture antibody.
Type image 7	E
Other Accession	NM_184234
Isotype	IgG2a Kappa
Antigen Source	Human: ~~ Positive
Target/Specificity	RNPC2 (NP_909122, 423 a.a. ~ 472 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
NCBI Accession	NP_001229528.1; NP_001229529.1; NP_004893.1; NP_909122.1
	Clone: 4G8
Org Accession	NP_909122
Gene Description	RNA binding motif protein 39
Gene Summary	The protein encoded by this gene is an RNA binding protein and possible splicing factor. The encoded protein is found in the nucleus, where it colocalizes with core spliceosomal proteins. Studies of a mouse protein with high sequence similarity to this protein suggest that this protein may act as a transcriptional coactivator for JUN/AP-1 and estrogen receptors. Multiple transcript variants encoding different isoforms have been observed for this gene. [provided by RefSeq

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Menge: 100 ug

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Lieferung vsl. bis 04.09.2025