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YY1 Antibody (monoclonal) (M05)

YY1 Antibody (monoclonal) (M05)

ArtNr	ABC-AT4566a
Hersteller	Abcepta
Menge	100 ug
Kategorie	Antibodies Primary Antibodies
Typ	Antibody Primary
Format	Clear, colorless solution in phosphate buffered saline, pH 7.2 .
Applikationen	WB, IF, ELISA
Clon	4C1
Specific against	other
Host	Mouse
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Similar products	YY1, INO80S, Transcriptional repressor protein YY1, Delta transcription factor, INO80 complex subunit S, NF-E1, Yin and yang 1, YY-1
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Primary Accession	P25490
Antigen Type	Recombinant Protein
Application	WB, IF, E
Bio Background	YY1 is a ubiquitously distributed transcription factor belonging to the GLI-Kruppel class of zinc finger proteins. The protein is involved in repressing and activating a diverse number of promoters. YY1 may direct histone deacetylases and histone acetyltransferases to a promoter in order to activate or repress the promoter, thus implicating histone modification in the function of YY1.
Bio References	CXCR4/YY1 inhibition impairs VEGF network and angiogenesis during malignancy. de Nigris F, et al. Proc Natl Acad Sci U S A, 2010 Aug 10. PMID 20660740.Transcription factor YY1 interacts with retroviral integrases and facilitates integration of moloney murine leukemia virus cDNA into the host chromosomes. Inayoshi Y, et al. J Virol, 2010 Aug. PMID 20519390.Repressors NFI and NFY participate in organ-specific regulation of von Willebrand factor promoter activity in transgenic mice. Nassiri M, et al. Arterioscler Thromb Vasc Biol, 2010 Jul. PMID 20431063.Identification of Yin Yang 1-interacting partners at -1026C/A in the human iNOS promoter. Li W, et al. Arch Biochem Biophys, 2010 Jun 15. PMID 20430007.Identification of a Smad4/YY1-recognized and BMP2-responsive transcriptional regulatory module in the promoter of mouse GABA transporter subtype I (Gat1) gene. Yao M, et al. J Neurosci, 2010 Mar 17. PMID 20237276.
Clonality	Monoclonal
Gene ID	7528
Gene Name	YY1
Subtitle	Mouse monoclonal antibody raised against a partial recombinant YY1.
Reactivity	H
Legend image 1	Immunofluorescence of monoclonal antibody to YY1 on HeLa cell. [antibody concentration 10 ug/ml]
Type image 1	IF
Legend image 2	Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (36.74 KDa) .
Type image 2	WB
Dilution image 2	1:500~1000
Legend image 3	YY1 monoclonal antibody (M05), clone 4C1 Western Blot analysis of YY1 expression in Hela S3 NE ( (Cat # AT4566a )
Type image 3	WB
Dilution image 3	1:500~1000
Legend image 4	Detection limit for recombinant GST tagged YY1 is approximately 0.03ng/ml as a capture antibody.
Type image 4	E
Other Accession	NM_003403
Isotype	IgG1 Kappa
Antigen Source	Human: ~~ Positive
Target/Specificity	YY1 (NP_003394, 221 a.a. ~ 320 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
NCBI Accession	NP_003394.1
	Clone: 4C1
Org Accession	NP_003394
Concentration	0.5mg/ml
Gene Description	YY1 transcription factor
Gene Summary	YY1 is a ubiquitously distributed transcription factor belonging to the GLI-Kruppel class of zinc finger proteins. The protein is involved in repressing and activating a diverse number of promoters. YY1 may direct histone deacetylases and histone acetyltransferases to a promoter in order to activate or repress the promoter, thus implicating histone modification in the function of YY1. [provided by RefSeq

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Menge: 100 ug

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