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TYSY Antibody (C-term)

TYSY Antibody (C-term)

ArtNr	ABC-AW5168-U100
Hersteller	Abcepta
Menge	100 ul
Kategorie	Antibodies Primary Antibodies
Typ	Antibody Primary
Format	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Applikationen	WB
Specific against	other
Host	Rabbit
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Similar products	TYMS; TS; Thymidylate synthase
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Primary Accession	P04818
Antigen Type	Synthetic Peptide
Application	WB
Bio Background	Thymidylate synthase catalyzes the methylation of deoxyuridylate to deoxythymidylate using 5, 10-methylenetetrahydrofolate (methylene-THF) as a cofactor. This function maintains the dTMP (thymidine-5-prime monophosphate) pool critical for DNA replication and repair. The enzyme has been of interest as a target for cancer chemotherapeutic agents. It is considered to be the primary site of action for 5-fluorouracil, 5-fluoro-2-prime-deoxyuridine, and some folate analogs.
Bio References	Ren, D.N., J Surg Oncol (2009) Schiffer, C.A., Biochemistry 34 (50), 16279-16287 (1995)
Clonality	Polyclonal
Gene ID	7298
Gene Name	TYMS
Subtitle	Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	H
Legend image 1	Western blot analysis of lysates from Jurkat, HL-60 cell line (from left to right), using TYSY Antibody (C-term)(Cat. #AW5168). AW5168 was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:5000 dilution was used as the secondary antibody.
Type image 1	WB
Dilution image 1	1:1000
Legend image 2	Western blot analysis of lysates from Jurkat, Hela cell line (from left to right), using TYSY Antibody (C-term)(Cat. #AW5168). AW5168 was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:10000 dilution was used as the secondary antibody.Lysates at 20ug per lane.
Type image 2	WB
Dilution image 2	1:1000
Predicted	M, Rat
Isotype	Rabbit Ig
Calculated MW	35716
Antigen Region	265-294
Antigen Source	HUMAN
Target/Specificity	This TYSY antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 265-294 amino acids from the C-terminal region of human TYSY.
NCBI Accession	NP_001062.1

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ABC-AW5168-U100-datasheet.pdf

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Menge: 100 ul

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Lieferung vsl. bis 02.10.2025

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