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IGF2BP2 Antibody (C-term)

IGF2BP2 Antibody (C-term)

ArtNr	ABC-AW5603-U100
Hersteller	Abcepta
Menge	100 ul
Kategorie	Antibodies Primary Antibodies
Typ	Antibody Primary
Applikationen	WB, FC, IHC-P
Specific against	other
Host	Rabbit
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Similar products	IGF2BP2, IMP2, IMP-2, VICKZ2, IGF-II mRNA-binding protein 2, Hepatocellular carcinoma autoantigen p62, IGF2 mRNA-binding protein 2, Insulin-like growth factor 2 mRNA-binding protein 2, VICKZ family member 2
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Primary Accession	Q9Y6M1
Antigen Type	Synthesized Peptide
Application	FC, IHC-P, WB
Bio Background	This gene encodes a member of the IGF-II mRNA-binding protein (IMP) family. The protein encoded by this gene contains several four KH domains and two RRM domains. It functions by binding to the 5' UTR of the insulin-like growth factor 2 (IGF2) mRNA and regulating IGF2 translation. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Bio References	Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010) Pechlivanis, S., et al. Arterioscler. Thromb. Vasc. Biol. 30(9):1867-1872(2010) Heni, M., et al. Diabetes (2010) In press : Rodriguez, S., et al. Growth Horm. IGF Res. 20(4):310-318(2010) Voight, B.F., et al. Nat. Genet. 42(7):579-589(2010)
Clonality	Polyclonal
Gene ID	10644
Gene Name	IGF2BP2
Subtitle	Affinity Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	H
Legend image 1	All lanes : Anti-IGF2BP2 Antibody (C-term) at 1:2000 dilution Lane 1: HepG2 whole cell lysate Lane 2: Hela whole cell lysate Lane 3: A549 whole cell lysate Lane 4: Raji whole cell lysate Lane 5: SH-SY5Y whole cell lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 66 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
Type image 1	WB
Dilution image 1	1:2000
Legend image 2	IGF2BP2 antibody(C-term) (Cat. #AW5603) immunohistochemistry analysis in formalin fixed and paraffin embedded human spleen tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the IGF2BP2 antibody(C-term) for immunohistochemistry. Clinical relevance has not been evaluated.
Type image 2	IHC-P
Dilution image 2	1:50~100
Legend image 3	IGF2BP2 Antibody (C-term) (Cat. #AW5603) flow cytometric analysis of HepG2 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Type image 3	FC
Dilution image 3	1:10~50
Other Accession	Q5SF07; Q5RB68
Predicted	M
Isotype	Rabbit Ig
Calculated MW	66121
Antigen Region	530-556
Antigen Source	HUMAN
Target/Specificity	This IGF2BP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 530-556 amino acids from the C-terminal region of human IGF2BP2.
NCBI Accession	NP_001007226.1; NP_006539.3

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Menge: 100 ul

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