Cytosolic K+ Channel-interacting Protein 1 (Kchip1)

Rabbit anti-Mouse cytosolic K+ channel-interacting protein1 (Kchip1) polyclonal antibody

A synthetic peptide (QTKQRRPSKDK) derived from the amino sequence amino acid 12-22 of mouse Kchip1, conjugated with KLH for immunization.

Protein G affinity purified

KChIP1 is an important member of the potassium channel interacting protein family. It binds to and influences the voltage gated potassium (Kv) channel. Like all other members in the family, KChIP1 has calcium binding domains (EF-hand-like) that sense calcium concentrations to regulate Kv channel. KChIP1 frequently forms complex with the rapid inactivating A-type Kv channels. It may play a role in modulating somatodendritic excitability, and the repolarization of cardiac myocytes following action potential. It is also reported that KChIP1 is associated with the GABAergic synapses in hippocampus.

Double distilled water is recommended to adjust the final concentration to 1.00 mg/mL.

Life science research, stem cell factor signalling, cancer research