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Anti-YY1 Antibody Picoband® (monoclonal, 2C10F9)

Anti-YY1 Antibody Picoband® (monoclonal, 2C10F9)

ArtNr	BOS-M00833-2
Hersteller	Boster
Menge	100 ug/vial
Quantity options	100 ug/vial 10 ug 100 ug 100 ug 100 ug 100 ug 100 ug 100 ug 100 ug 100 ug 100 ug 100 ug
Kategorie	Antibodies Flow Cytometry Immunohistochemistry Western Blot Primary Antibodies
Typ	Antibody Monoclonal
Format	Lyophilized
Applikationen	WB, FC, IHC
Clon	2C10F9
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Mouse
Isotype	IgG2a
Sensitivity	>5000 cells
Citations	1. Shi Y, Seto E, Chang LS, Shenk T (Oct 1991). Transcriptional repression by YY1, a human GLI-Krüppel-related protein, and relief of repression by adenovirus E1A protein. Cell 67 (2): 377–88. 2. Thiaville MM, Kim J (2011). Oncogenic potential of yin yang 1 mediated through control of imprinted genes. Critical Reviews in Oncogenesis 16 (3-4): 199–209. 3. Zhu W, Lossie AC, Camper SA, Gumucio DL (Apr 1994). Chromosomal localization of the transcription factor YY1 in the mouse and human. Mammalian Genome 5 (4): 234–6.
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	Dihydrofolate reductase,DHFR
Lieferbar
Manufacturer - Category	Primary Antibodies
Storage Conditions	At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
Observed Molecular weight	65 kDa
Clonality	Monoclonal
Application Details	Western blot, 0.25-0.5 μg/ml, Human, Mouse, Rat Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/ml, Human Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
Gene Name	YY1
Gene Full Name	dihydrofolate reductase
Manufacturer - Specificity	No cross-reactivity with other proteins.
Background	YY1 (Yin Yang 1) is a transcriptional repressor protein in humans that is encoded by the YY1 gene. YY1 is a ubiquitously distributed transcription factor belonging to the GLI-Kruppel class of zinc finger proteins. The protein is involved in repressing and activating a diverse number of promoters. YY1 may histone deacetylases and histone acetyltransferases to a promoter in order to activate or repress the promoter, thus implicating histone modification in the function of YY1.
Immunogen	A synthetic peptide corresponding to a sequence in the middle region of human YY1, identical to the related mouse sequence.
Contents	Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.
Purification	Immunogen affinity purified.
Reconstitution	Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.
Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.
Manufacturer - Research Category	Amino Acid Metabolism, Amino Acids, Cancer, Cell Biology, Metabolic Signaling Pathways, Metabolism, Nucleotide Metabolism, Pathways and Processes, Signal Transduction
Protein Name	zeta chain of T cell receptor associated protein kinase 70
Protein Function	Key enzyme in folate metabolism. Contributes to the de novo mitochondrial thymidylate biosynthesis pathway. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. Binds its own mRNA and that of DHFR2.
Subcellular Localization	Mitochondrion. Cytoplasm
Description	Boster Bio Anti-YY1 Antibody Picoband® (monoclonal, 2C10F9) catalog # M00833-2. Tested in Flow Cytometry, IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Tissue Specificity	Widely expressed in fetal and adult tissues, including throughout the fetal and adult brains and whole blood. Expression is higher in the adult brain than in the fetal brain.
Manufacturer - Cross Reactivity	No cross-reactivity with other proteins.

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BOS-M00833-2-datasheet.pdf

BOS-M00833-2-safety-datasheet.pdf