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HIPK3 Antibody

ArtNr CSB-PA872492LA01HU-50ug
Hersteller Cusabio
Menge 50 ug
Quantity options 100 ug 20 ug 50 ug
Kategorie
Typ Antibody Polyclonal
Format Liquid
Applikationen IF, IHC, ELISA
Specific against Human (Homo sapiens)
Host Rabbit
Isotype IgG
Konjugat/Tag Unconjugated
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias Androgen receptor interacting nuclear protein kinase antibody; Androgen receptor-interacting nuclear protein kinase antibody; ANPK antibody; DYRK6 antibody; Fas interacting serine/threonine protein kinase antibody; Fas-interacting serine/threonine-protein kinase antibody; FIST antibody; FIST3 antibody; Hipk3 antibody; HIPK3_HUMAN antibody; homeodomain interacting protein kinase 3 antibody; Homeodomain-interacting protein kinase 3 antibody; Homolog of protein kinase YAK1 antibody; PKY antibody; RP24 297H17.5 antibody; YAK1 antibody
Similar products HIPK3, Homeodomain-interacting protein kinase 3 (EC 2.7.11.1) (Androgen receptor-interacting nuclear protein kinase) (ANPK) (Fas-interacting serine/threonine-protein kinase) (FIST) (Homolog of protein kinase YAK1), DYRK6 FIST3 PKY
Lieferbar
Manufacturer - Type
Polyclonal Antibody
Manufacturer - Targets
HIPK3
Storage Conditions
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Manufacturer - Alias
Androgen receptor interacting nuclear protein kinase antibody; Androgen receptor-interacting nuclear protein kinase antibody; ANPK antibody; DYRK6 antibody; Fas interacting serine/threonine protein kinase antibody; Fas-interacting serine/threonine-protein kinase antibody; FIST antibody; FIST3 antibody; Hipk3 antibody; HIPK3_HUMAN antibody; homeodomain interacting protein kinase 3 antibody; Homeodomain-interacting protein kinase 3 antibody; Homolog of protein kinase YAK1 antibody; PKY antibody; RP24 297H17.5 antibody; YAK1 antibody
Immunogen Species
Human
Immunogen
Recombinant Human Homeodomain-interacting protein kinase 3 protein (841-1130AA)
Dilution
ELISA:1:2000-1:10000
IHC:1:20-1:200
IF:1:50-1:200
Background
Serine/threonine-protein kinase involved in transcription regulation, apoptosis and steroidogenic gene expression. Phosphorylates JUN and RUNX2. Seems to negatively regulate apoptosis by promoting FADD phosphorylation. Enhances androgen receptor-mediated transcription. May act as a transcriptional corepressor for NK homeodomain transcription factors. The phosphorylation of NR5A1 activates SF1 leading to increased steroidogenic gene expression upon cAMP signaling pathway stimulation. In osteoblasts, supports transcription activation: phosphorylates RUNX2 that synergizes with SPEN/MINT to enhance FGFR2-mediated activation of the osteocalcin FGF-responsive element (OCFRE).
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Purification Method
>95%, Protein G purified
General Research Areas
Cell Biology
Initial Research Areas
Cell Biology
Antigen Species
Human
Antigen
Recombinant Human Homeodomain-interacting protein kinase 3 protein (841-1130AA)
Clonality
Polyclonal

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 50 ug
Lieferbar: In stock
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