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HIPK3 Antibody

HIPK3 Antibody

Item no.	CSB-PA872492LA01HU-50ug
Manufacturer	Cusabio
Amount	50 ug
Quantity options	100 ug 20 ug 50 ug
Category	Oncology Antibodies By Cell Type Carcinoma Immunohistochemistry ELISA Immunofluorescence Primary Antibodies
Type	Antibody Polyclonal
Format	Liquid
Applications	IF, IHC, ELISA
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
Conjugate/Tag	Unconjugated
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Androgen receptor interacting nuclear protein kinase antibody; Androgen receptor-interacting nuclear protein kinase antibody; ANPK antibody; DYRK6 antibody; Fas interacting serine/threonine protein kinase antibody; Fas-interacting serine/threonine-protein kinase antibody; FIST antibody; FIST3 antibody; Hipk3 antibody; HIPK3_HUMAN antibody; homeodomain interacting protein kinase 3 antibody; Homeodomain-interacting protein kinase 3 antibody; Homolog of protein kinase YAK1 antibody; PKY antibody; RP24 297H17.5 antibody; YAK1 antibody
Similar products	HIPK3, Homeodomain-interacting protein kinase 3 (EC 2.7.11.1) (Androgen receptor-interacting nuclear protein kinase) (ANPK) (Fas-interacting serine/threonine-protein kinase) (FIST) (Homolog of protein kinase YAK1), DYRK6 FIST3 PKY
Available
Manufacturer - Type	Polyclonal Antibody
Manufacturer - Targets	HIPK3
Storage Conditions	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Manufacturer - Alias	Androgen receptor interacting nuclear protein kinase antibody; Androgen receptor-interacting nuclear protein kinase antibody; ANPK antibody; DYRK6 antibody; Fas interacting serine/threonine protein kinase antibody; Fas-interacting serine/threonine-protein kinase antibody; FIST antibody; FIST3 antibody; Hipk3 antibody; HIPK3_HUMAN antibody; homeodomain interacting protein kinase 3 antibody; Homeodomain-interacting protein kinase 3 antibody; Homolog of protein kinase YAK1 antibody; PKY antibody; RP24 297H17.5 antibody; YAK1 antibody
Immunogen Species	Human
Immunogen	Recombinant Human Homeodomain-interacting protein kinase 3 protein (841-1130AA)
Dilution	ELISA:1:2000-1:10000 IHC:1:20-1:200 IF:1:50-1:200
Background	Serine/threonine-protein kinase involved in transcription regulation, apoptosis and steroidogenic gene expression. Phosphorylates JUN and RUNX2. Seems to negatively regulate apoptosis by promoting FADD phosphorylation. Enhances androgen receptor-mediated transcription. May act as a transcriptional corepressor for NK homeodomain transcription factors. The phosphorylation of NR5A1 activates SF1 leading to increased steroidogenic gene expression upon cAMP signaling pathway stimulation. In osteoblasts, supports transcription activation: phosphorylates RUNX2 that synergizes with SPEN/MINT to enhance FGFR2-mediated activation of the osteocalcin FGF-responsive element (OCFRE).
Buffer	Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Purification Method	>95%, Protein G purified
General Research Areas	Cell Biology
Initial Research Areas	Cell Biology
Antigen Species	Human
Antigen	Recombinant Human Homeodomain-interacting protein kinase 3 protein (841-1130AA)
Clonality	Polyclonal

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 50 ug

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Delivery expected until 9/25/2025

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